"Ethacrynic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
Concept/Terms
Ethacrynic Acid- Ethacrynic Acid
- Acid, Ethacrynic
- Etacrynic Acid
- Acid, Etacrynic
- Ethacrinic Acid
- Acid, Ethacrinic
Below are MeSH descriptors whose meaning is more general than "Ethacrynic Acid".
Below are MeSH descriptors whose meaning is more specific than "Ethacrynic Acid".
This graph shows the total number of publications written about "Ethacrynic Acid" by people in Harvard Catalyst Profiles by year, and whether "Ethacrynic Acid" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Ethacrynic Acid" by people in Profiles.
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A Switch-On Affinity-Based Iridium(III) Conjugate Probe for Imaging Mitochondrial Glutathione S-Transferase in Breast Cancer Cells. Bioconjug Chem. 2023 10 18; 34(10):1727-1737.
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Potent anti-proliferative actions of a non-diuretic glucosamine derivative of ethacrynic acid. Bioorg Med Chem Lett. 2016 06 15; 26(12):2829-2833.
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Healing the orphaned heart: heart failure in a patient with glucose-6-phosphate dehydrogenase deficiency. BMJ Case Rep. 2015 Mar 05; 2015.
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The phase 2 enzyme inducers ethacrynic acid, DL-sulforaphane, and oltipraz inhibit lipopolysaccharide-induced high-mobility group box 1 secretion by RAW 264.7 cells. J Pharmacol Exp Ther. 2006 Mar; 316(3):1070-9.
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Ethacrynic acid inhibits multiple steps in the NF-kappaB signaling pathway. Shock. 2005 Jan; 23(1):45-53.
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Ethacrynic acid increases facility of outflow in the human eye in vitro. Arch Ophthalmol. 1992 Jan; 110(1):106-9.
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Initial observations of rabbit retinal pigment epithelium-choroid-sclera preparations. Invest Ophthalmol Vis Sci. 1988 May; 29(5):814-7.
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Water and electrolyte balance in protoscoleces of Echinococcus granulosus incubated in vitro: effect of metabolic inhibitors. Int J Parasitol. 1981 Oct; 11(5):405-10.
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Ultrastructural histopathology in a case of human ototoxicity due to loop diuretics. Acta Otolaryngol. 1981 May-Jun; 91(5-6):399-414.
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Temporal bone histopathology in human ototoxicity due to loop diuretics. Scand Audiol Suppl. 1981; 14 Suppl:201-13.