16,16-Dimethylprostaglandin E2

"16,16-Dimethylprostaglandin E2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and growth of experimental tumors.

Descriptor ID

D015064

MeSH Number(s)

D10.251.355.255.550.700.450.300

D23.469.700.660.200

Concept/Terms

16,16-Dimethylprostaglandin E2

Below are MeSH descriptors whose meaning is more general than "16,16-Dimethylprostaglandin E2".

Chemicals and Drugs [D]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Eicosanoids [D10.251.355.255]
Prostaglandins [D10.251.355.255.550]
Prostaglandins, Synthetic [D10.251.355.255.550.700]
Prostaglandins E, Synthetic [D10.251.355.255.550.700.450]
16,16-Dimethylprostaglandin E2 [D10.251.355.255.550.700.450.300]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Prostaglandins, Synthetic [D23.469.700]
Prostaglandins E, Synthetic [D23.469.700.660]
16,16-Dimethylprostaglandin E2 [D23.469.700.660.200]

Below are MeSH descriptors whose meaning is related to "16,16-Dimethylprostaglandin E2".

Below are MeSH descriptors whose meaning is more specific than "16,16-Dimethylprostaglandin E2".

publications

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This graph shows the total number of publications written about "16,16-Dimethylprostaglandin E2" by people in Harvard Catalyst Profiles by year, and whether "16,16-Dimethylprostaglandin E2" was a major or minor topic of these publication.

Below are the most recent publications written about "16,16-Dimethylprostaglandin E2" by people in Profiles.

PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo. Exp Hematol. 2017 12; 56:64-68.

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Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles. Proc Natl Acad Sci U S A. 2016 May 17; 113(20):5552-7.

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Translational research: the path for bringing discovery to patients. Cell Stem Cell. 2014 Feb 06; 14(2):146-8.

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Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 2013 Oct 24; 122(17):3074-81.

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The effect of eicosanoids on the expression of MHC genes in cultured human colon cancer cells and mouse colonocytes in vivo. Prostaglandins Leukot Essent Fatty Acids. 1996 Dec; 55(6):373-8.

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The influence of exogenous eicosanoids on the radiation response of cultured bovine aortic endothelial cells. Radiat Res. 1991 Jan; 125(1):41-7.

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Intragraft delivery of 16, 16-dimethyl PGE2 induces donor-specific tolerance in rat cardiac allograft recipients. Transplantation. 1991 Jan; 51(1):242-6.

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Prostaglandin E2 inhibits in vitro and in vivo lymphocyte responses in allogeneic transplantation. Ann Thorac Surg. 1990 Jun; 49(6):927-30; discussion 931.

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Protection of gastric mucosa against hypertonic sodium chloride by 16,16-dimethyl prostaglandin E2 or sodium thiosulfate in the rat: evidence for decreased mucosal penetration of damaging agent. Dig Dis Sci. 1989 Dec; 34(12):1865-72.

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The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat. Hepatology. 1989 Nov; 10(5):801-6.

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