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Maturation-Promoting Factor

"Maturation-Promoting Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
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Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.


publications
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This graph shows the total number of publications written about "Maturation-Promoting Factor" by people in Harvard Catalyst Profiles by year, and whether "Maturation-Promoting Factor" was a major or minor topic of these publication.
Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 1994 and 1995 and 1997 and 1998 and 2005 and 2007
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.