Dimethylnitrosamine

"Dimethylnitrosamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties. It causes serious liver damage and is a hepatocarcinogen in rodents.

Descriptor ID

D004128

MeSH Number(s)

D02.654.442.225

Concept/Terms

Dimethylnitrosamine

Below are MeSH descriptors whose meaning is more general than "Dimethylnitrosamine".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Nitroso Compounds [D02.654]
Nitrosamines [D02.654.442]
Dimethylnitrosamine [D02.654.442.225]

Below are MeSH descriptors whose meaning is related to "Dimethylnitrosamine".

Below are MeSH descriptors whose meaning is more specific than "Dimethylnitrosamine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dimethylnitrosamine" by people in Harvard Catalyst Profiles by year, and whether "Dimethylnitrosamine" was a major or minor topic of these publication.

Bar chart showing 7 publications over 7 distinct years, with a maximum of 1 publications in 1996 and 1998 and 2000 and 2009 and 2012 and 2020 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	1	0	1
2000	0	1	1
2009	1	0	1
2012	1	0	1
2020	1	0	1
2021	0	1	1

Below are the most recent publications written about "Dimethylnitrosamine" by people in Profiles.

Ranitidine Use and Risk of Upper Gastrointestinal Cancers. Cancer Epidemiol Biomarkers Prev. 2021 12; 30(12):2302-2308.

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The Finding of N-Nitrosodimethylamine in Common Medicines. Oncologist. 2020 06; 25(6):460-462.

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Hepatic stellate cell-targeted delivery of hepatocyte growth factor transgene via bile duct infusion enhances its expression at fibrotic foci to regress dimethylnitrosamine-induced liver fibrosis. Hum Gene Ther. 2013 May; 24(5):508-19.

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Effect of sinapic acid against dimethylnitrosamine-induced hepatic fibrosis in rats. Arch Pharm Res. 2013 May; 36(5):608-18.

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Matrix metalloproteinase-9, -10, and -12, MDM2 and p53 expression in mouse liver during dimethylnitrosamine-induced oxidative stress and genomic injury. Mol Cell Biochem. 2012 Jun; 365(1-2):351-61.

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Mechanistic basis for the chemopreventive effects of black raspberries at a late stage of rat esophageal carcinogenesis. Mol Carcinog. 2011 Apr; 50(4):291-300.

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Multiple berry types prevent N-nitrosomethylbenzylamine-induced esophageal cancer in rats. Pharm Res. 2010 Jun; 27(6):1138-45.

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Prospective study of meat intake and dietary nitrates, nitrites, and nitrosamines and risk of adult glioma. Am J Clin Nutr. 2009 Sep; 90(3):570-7.

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Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development. Cancer Cell. 2007 Mar; 11(3):275-89.

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Functional role of cytochrome p-450 2a3 in N-nitrosomethylbenzylamine metabolism in rat esophagus. J Toxicol Environ Health A. 2002 Aug 09; 65(15):1077-91.

View in: PubMed

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