Antidepressive Agents, Tricyclic
"Antidepressive Agents, Tricyclic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
MeSH Number(s)
D27.505.954.427.700.122.055
Concept/Terms
Antidepressive Agents, Tricyclic- Antidepressive Agents, Tricyclic
- Antidepressant Drugs, Tricyclic
- Drugs, Tricyclic Antidepressant
- Tricyclic Antidepressant Drugs
- Antidepressants, Tricyclic
- Tricyclic Antidepressants
- Tricyclic Antidepressive Agents
- Agents, Tricyclic Antidepressive
Below are MeSH descriptors whose meaning is more general than "Antidepressive Agents, Tricyclic".
Below are MeSH descriptors whose meaning is more specific than "Antidepressive Agents, Tricyclic".
This graph shows the total number of publications written about "Antidepressive Agents, Tricyclic" by people in Harvard Catalyst Profiles by year, and whether "Antidepressive Agents, Tricyclic" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 3 | 3 | 6 |
1995 | 5 | 3 | 8 |
1996 | 4 | 3 | 7 |
1997 | 6 | 1 | 7 |
1998 | 9 | 5 | 14 |
1999 | 4 | 4 | 8 |
2000 | 4 | 8 | 12 |
2001 | 6 | 3 | 9 |
2002 | 5 | 5 | 10 |
2003 | 12 | 5 | 17 |
2004 | 6 | 3 | 9 |
2005 | 5 | 7 | 12 |
2006 | 3 | 4 | 7 |
2007 | 8 | 5 | 13 |
2008 | 4 | 2 | 6 |
2009 | 6 | 1 | 7 |
2010 | 1 | 6 | 7 |
2011 | 0 | 4 | 4 |
2012 | 1 | 4 | 5 |
2013 | 1 | 3 | 4 |
2014 | 4 | 5 | 9 |
2015 | 4 | 3 | 7 |
2016 | 2 | 1 | 3 |
2017 | 3 | 3 | 6 |
2018 | 3 | 1 | 4 |
2019 | 0 | 2 | 2 |
2020 | 2 | 3 | 5 |
2021 | 1 | 2 | 3 |
2022 | 1 | 2 | 3 |
2023 | 0 | 1 | 1 |
2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Antidepressive Agents, Tricyclic" by people in Profiles.
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Antidepressant discontinuation patterns and characteristics across sociodemographic groups in the United States. J Affect Disord. 2024 Jun 15; 355:82-85.
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QTc Intervals in Drug Poisoning Patients With Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors: Erratum. Am J Ther. 2023 Jan-Feb 01; 30(1):e93.
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AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Constipation. Gastroenterology. 2022 07; 163(1):118-136.
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AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea. Gastroenterology. 2022 07; 163(1):137-151.
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Doctors Speak: A Qualitative Study of Physicians' Prescribing of Antidepressants in Functional Bowel Disorders. Cult Med Psychiatry. 2023 Sep; 47(3):669-683.
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Improving Medication Tolerance: A Pilot Study in Disorders of Gut-brain Interaction Treated With Tricyclic Antidepressants. J Clin Gastroenterol. 2022 May-Jun 01; 56(5):452-456.
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Oral and Topical Treatment of Painful Diabetic Polyneuropathy: Practice Guideline Update Summary: Report of the AAN Guideline Subcommittee. Neurology. 2022 01 04; 98(1):31-43.
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Electrocardiogram Before Tricyclic Antidepressant Use: Minimal Impact in Pediatric Functional Gastrointestinal Disorders. J Pediatr Gastroenterol Nutr. 2021 10 01; 73(4):523-528.
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Tricyclic antidepressants versus 'active placebo', placebo or no intervention for adults with major depressive disorder: a protocol for a systematic review with meta-analysis and Trial Sequential Analysis. Syst Rev. 2021 08 13; 10(1):227.
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FRAMES protocol versus simple advice for medication-overuse headache: a prospective, randomized, controlled clinical trial. Acta Neurol Belg. 2021 Oct; 121(5):1259-1264.