Harvard Catalyst Profiles

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Histamine H1 Antagonists, Non-Sedating

"Histamine H1 Antagonists, Non-Sedating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.


This graph shows the total number of publications written about "Histamine H1 Antagonists, Non-Sedating" by people in Harvard Catalyst Profiles by year, and whether "Histamine H1 Antagonists, Non-Sedating" was a major or minor topic of these publication.
Bar chart showing 12 publications over 8 distinct years, with a maximum of 3 publications in 2007
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.