"Endodermal Sinus Tumor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)
Concept/Terms
Endodermal Sinus Tumor- Endodermal Sinus Tumor
- Endodermal Sinus Tumors
- Tumor, Endodermal Sinus
- Tumors, Endodermal Sinus
- Yolk Sac Tumor
- Tumor, Yolk Sac
- Tumors, Yolk Sac
- Yolk Sac Tumors
Below are MeSH descriptors whose meaning is more general than "Endodermal Sinus Tumor".
Below are MeSH descriptors whose meaning is more specific than "Endodermal Sinus Tumor".
This graph shows the total number of publications written about "Endodermal Sinus Tumor" by people in Harvard Catalyst Profiles by year, and whether "Endodermal Sinus Tumor" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 2 | 1 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 1 | 3 |
| 2022 | 6 | 0 | 6 |
| 2023 | 1 | 0 | 1 |
Below are the most recent publications written about "Endodermal Sinus Tumor" by people in Profiles.
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FoxA2 is a reliable marker for the diagnosis of yolk sac tumour postpubertal-type. Histopathology. 2023 Sep; 83(3):465-476.
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Addressing the diagnostic and therapeutic dilemmas of ovarian immature teratoma: Report from a clinicopathologic consensus conference. Eur J Cancer. 2022 09; 173:59-70.
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A Subset of SMARCB1 (INI-1)-deficient vulvar neoplasms express germ cell markers. Histopathology. 2022 Sep; 81(3):342-351.
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Pathologic findings and clinical outcomes in patients who required neoadjuvant chemotherapy before orchiectomy for testicular germ cell tumors. Hum Pathol. 2022 10; 128:48-55.
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Sarcomatoid Yolk Sac Tumor Harbors Somatic Mutations That Are Otherwise Rare in Testicular Germ Cell Tumors. Am J Surg Pathol. 2022 05 01; 46(5):701-712.
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Malignant Gonadal Germ Cell Tumors (Other Than Pure Germinoma) in Patients With Disorders of Sex Development: A Report of 21 Cases Based Largely on the Collection of Dr Robert E. Scully, Illustrating a High Frequency of Yolk Sac Tumor With Prominent Hepatoid and Glandular Features. Am J Surg Pathol. 2022 05 01; 46(5):664-676.
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Yolk Sac Tumor of the Ovary: A Report of 150 Cases and Review of the Literature. Am J Surg Pathol. 2022 03 01; 46(3):309-325.
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Vulvar Yolk Sac Tumors Are Somatically Derived SMARCB1 (INI-1)-Deficient Neoplasms. Am J Surg Pathol. 2022 02 01; 46(2):169-178.
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Pitfalls in the diagnosis of yolk sac tumor: Lessons from a clinical trial. Pediatr Blood Cancer. 2022 02; 69(2):e29451.
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Malignant Mixed Germ Cell Tumors of the Ovary: An Analysis of 100 Cases Emphasizing the Frequency and Interrelationships of Their Tumor Types. Am J Surg Pathol. 2021 06 01; 45(6):727-741.