Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Procollagen-Proline Dioxygenase

"Procollagen-Proline Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl-containing-peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES.


This graph shows the total number of publications written about "Procollagen-Proline Dioxygenase" by people in Harvard Catalyst Profiles by year, and whether "Procollagen-Proline Dioxygenase" was a major or minor topic of these publication.
Bar chart showing 44 publications over 20 distinct years, with a maximum of 7 publications in 2009
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.