D011401Chemicals & DrugsG02.111.570.080.689.675G05.360.080.689.675G05.360.340.024.340.137.750.680194458630.425115Promoter Regions, Geneticcatalyst:eCommonsLogineCommons LoginFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson4.511640.001938741944research area of0.9430460.01330747448subject area forMedicineHematology/OncologyRheumatologyBeth Israel Deaconess Medical CenterHarvard Medical SchoolKS26KevinStruhlKevin Struhl, Ph.D.42.33588600000000-71.1051460000000013584Struhl, KevinDavid Wesley Gaiser Professor of Biological Chemistry and Molecular PharmacologyWCA2WilliamAirdWilliam Cameron Aird, M.D.42.34022770000000-71.105854000000009537Aird, WilliamProfessor of MedicineGT33GeorgeTsokosGeorge C. Tsokos, M.D.42.34022770000000-71.1058540000000037050Tsokos, GeorgeProfessor of MedicineDGT1DanielTenenDaniel Geoffrey Tenen, M.D.42.33837200000000-71.1032690000000063164Tenen, DanielProfessor of Medicinetrue1Professor of MedicineProfessor of Medicinetrue1Professor of MedicineProfessor of Medicinetrue1Professor of MedicineProfessor of Medicinetrue1David Wesley Gaiser Professor of Biological Chemistry and Molecular PharmacologyDavid Wesley Gaiser Professor of Biological Chemistry and Molecular PharmacologyBCMP35389777Dietlein F, Wang AB, Fagre C, Tang A, Besselink NJM, Cuppen E, Li C, Sunyaev SR, Neal JT, Van Allen EMScience (New York, N.Y.)Genome-wide analysis of somatic noncoding mutation patterns in cancer. Science. 2022 04 08; 376(6589):eabg5601.Science2022-04-08T00:00:002022Genome-wide analysis of somatic noncoding mutation patterns in cancer.35594906Bergman DT, Jones TR, Liu V, Ray J, Jagoda E, Siraj L, Kang HY, Nasser J, Kane M, Rios A, Nguyen TH, Grossman SR, Fulco CP, Lander ES, Engreitz JMNatureCompatibility rules of human enhancer and promoter sequences. Nature. 2022 07; 607(7917):176-184.Nature2022-05-20T00:00:002022Compatibility rules of human enhancer and promoter sequences.36630508Chen GD, Fatima I, Xu Q, Rozhkova E, Fessing MY, Mardaryev AN, Sharov AA, Xu GL, Botchkarev VAScience advancesDNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation. Sci Adv. 2023 01 13; 9(2):eabo7605.Sci Adv2023-01-11T00:00:002023DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation.true1Edward S. Harkness Professor of Biological Chemistry and Molecular PharmacologyEdward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology37070176Antwi EB, Marrakchi Y, Çiçek Ö, Brox T, Di Ventura BNucleic acids researchRequirements for mammalian promoters to decode transcription factor dynamics. Nucleic Acids Res. 2023 05 22; 51(9):4674-4690.Nucleic Acids Res2023-05-22T00:00:002023Requirements for mammalian promoters to decode transcription factor dynamics.36356143Chun-On P, Hinchie AM, Beale HC, Gil Silva AA, Rush E, Sander C, Connelly CJ, Seynnaeve BKN, Kirkwood JM, Vaske OM, Greider CW, Alder JKScience (New York, N.Y.)TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma. Science. 2022 Nov 11; 378(6620):664-668.Science2022-11-10T00:00:002022TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma.KA140KarenAdelmanKaren Adelman, Ph.D.149926Adelman, KarenEdward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology0Full Professor