Harvard Catalyst Profiles

Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.

Below are MeSH descriptors whose meaning is more general than "Polyendocrinopathies, Autoimmune".

Below are MeSH descriptors whose meaning is related to "Polyendocrinopathies, Autoimmune".

Below are MeSH descriptors whose meaning is more specific than "Polyendocrinopathies, Autoimmune".