Limulus Test

"Limulus Test" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.

Descriptor ID

D008033

MeSH Number(s)

E01.370.225.124.470

E01.370.225.875.150.570

E05.091.570

E05.200.124.470

E05.200.875.150.570

Concept/Terms

Limulus Test

Below are MeSH descriptors whose meaning is more general than "Limulus Test".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Biological Assay [E05.091]
Limulus Test [E05.091.570]
Clinical Laboratory Techniques [E05.200]
Microbiological Techniques [E05.200.875]
Bacteriological Techniques [E05.200.875.150]
Limulus Test [E05.200.875.150.570]

Below are MeSH descriptors whose meaning is related to "Limulus Test".

Below are MeSH descriptors whose meaning is more specific than "Limulus Test".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Limulus Test" by people in Harvard Catalyst Profiles by year, and whether "Limulus Test" was a major or minor topic of these publication.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 1998 and 2005 and 2007 and 2012 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
2005	0	1	1
2007	0	1	1
2012	0	1	1
2018	0	1	1

Below are the most recent publications written about "Limulus Test" by people in Profiles.

Successful and failed mini-implants: microbiological evaluation and quantification of bacterial endotoxin. J Appl Oral Sci. 2018 Jul 10; 26:e20170631.

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Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders. J Exp Med. 2014 Sep 22; 211(10):2033-45.

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Interleukin-8 induces an elevation in the endotoxin activity assay (EAA) level: does the EAA truly measure the endotoxin level? J Infect Chemother. 2013 Oct; 19(5):825-32.

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Evaluation of an endotoxin-specific limulus amebocyte lysate assay using leukocyte-rich plasma for the diagnosis of gram-negative bacterial infection. J Infect Chemother. 2013 Apr; 19(2):299-304.

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[Study on the leukocyte-rich plasma as the specimen for the measurement of endotoxin]. Rinsho Byori. 2012 Nov; 60(11):1045-52.

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Detection of microbial translocation in HIV and SIV infection using the Limulus amebocyte lysate assay is masked by serum and plasma. PLoS One. 2012; 7(8):e41258.

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Innate immune activation in neonatal tracheal aspirates suggests endotoxin-driven inflammation. Pediatr Res. 2012 Aug; 72(2):203-11.

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Experimental application of a synthetic luminescent substrate assay using endotoxin-specific limulus amebocyte lysate to human blood. J Infect Chemother. 2012 Jun; 18(3):370-7.

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Simplified preparation of crude and functional coagulogen by thermal inactivation of serine proteases in Limulus amebocyte lysate and its application for rapid endotoxin determination. J Biosci Bioeng. 2012 Mar; 113(3):406-11.

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Development of an electrochemical Limulus amebocyte lysate assay technique for portable and highly sensitive endotoxin sensor. Innate Immun. 2012 Apr; 18(2):343-9.

View in: PubMed

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