Mixed Connective Tissue Disease

"Mixed Connective Tissue Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.

Descriptor ID

D008947

MeSH Number(s)

C17.300.540

Concept/Terms

Mixed Connective Tissue Disease

Below are MeSH descriptors whose meaning is more general than "Mixed Connective Tissue Disease".

Diseases [C]
Skin and Connective Tissue Diseases [C17]
Connective Tissue Diseases [C17.300]
Mixed Connective Tissue Disease [C17.300.540]

Below are MeSH descriptors whose meaning is related to "Mixed Connective Tissue Disease".

Below are MeSH descriptors whose meaning is more specific than "Mixed Connective Tissue Disease".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mixed Connective Tissue Disease" by people in Harvard Catalyst Profiles by year, and whether "Mixed Connective Tissue Disease" was a major or minor topic of these publication.

Bar chart showing 14 publications over 9 distinct years, with a maximum of 3 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	0	1
2002	2	0	2
2011	1	1	2
2013	1	1	2
2014	3	0	3
2017	1	0	1
2018	0	1	1
2020	0	1	1
2023	1	0	1

Below are the most recent publications written about "Mixed Connective Tissue Disease" by people in Profiles.

Hyaluronidase Injections for Oral Microstomia in Systemic Sclerosis and Mixed Connective Tissue Disease. JAMA Dermatol. 2023 12 01; 159(12):1393-1395.

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Worldwide trends in all-cause mortality of auto-immune systemic diseases between 2001 and 2014. Autoimmun Rev. 2020 Jun; 19(6):102531.

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Drop Head Syndrome as a Rare Complication in Mixed Connective Tissue Disease. Intern Med. 2020 Mar 01; 59(5):729-732.

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Brief Report: How Do Patients With Newly Diagnosed Systemic Lupus Erythematosus Present? A Multicenter Cohort of Early Systemic Lupus Erythematosus to Inform the Development of New Classification Criteria. Arthritis Rheumatol. 2019 01; 71(1):91-98.

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An unusual association between hemophagocytic lymphohistiocytosis, mixed connective tissue disease, and autoimmune hemolytic anemia: A case report. Medicine (Baltimore). 2017 Jul; 96(28):e7488.

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Treatment of Vasodilator-resistant Mixed Connective Tissue Disease-associated Pulmonary Arterial Hypertension with Glucocorticoid and Cyclophosphamide. Intern Med. 2017; 56(4):445-448.

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Case 9-2014: A woman with increasing dyspnea. N Engl J Med. 2014 07 24; 371(4):388-9.

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Impaired endothelial function in patients with undifferentiated connective tissue disease: a follow-up study. Rheumatology (Oxford). 2014 Nov; 53(11):2035-43.

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Case records of the Massachusetts General Hospital. Case 9-2014. A 34-year-old woman with increasing dyspnea. N Engl J Med. 2014 Mar 20; 370(12):1149-57.

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Rapid progression to pulmonary arterial hypertension crisis associated with mixed connective tissue disease in an 11-year-old girl. Eur J Pediatr. 2013 Sep; 172(9):1263-5.

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