Pyruvate Dehydrogenase (Lipoamide)-Phosphatase
"Pyruvate Dehydrogenase (Lipoamide)-Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
(Pyruvate dehydrogenase (lipoamide))-phosphate phosphohydrolase. A mitochondrial enzyme that catalyzes the hydrolytic removal of a phosphate on a specific seryl hydroxyl group of pyruvate dehydrogenase, reactivating the enzyme complex. EC 3.1.3.43.
MeSH Number(s)
D08.811.277.352.650.625.725
Concept/Terms
Pyruvate Dehydrogenase (Lipoamide)-Phosphatase- Pyruvate Dehydrogenase (Lipoamide)-Phosphatase
- PDH Phosphatase
- Phosphatase, PDH
- Pyruvate Dehydrogenase Phosphatase
- Phosphatase, Pyruvate Dehydrogenase
- Pyruvate Dehydrogenase Phosphate Phosphatase
Below are MeSH descriptors whose meaning is more general than "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase".
Below are MeSH descriptors whose meaning is more specific than "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase".
This graph shows the total number of publications written about "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase" by people in Harvard Catalyst Profiles by year, and whether "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase" was a major or minor topic of these publication.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
Below are the most recent publications written about "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase" by people in Profiles.
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Association of structural variation with cardiometabolic traits in Finns. Am J Hum Genet. 2021 04 01; 108(4):583-596.
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FOXK1 and FOXK2 regulate aerobic glycolysis. Nature. 2019 02; 566(7743):279-283.
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1a,25-Dihydroxyvitamin D3 Regulates Mitochondrial Oxygen Consumption and Dynamics in Human Skeletal Muscle Cells. J Biol Chem. 2016 Jan 15; 291(3):1514-28.
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Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth. J Biol Chem. 2014 Aug 01; 289(31):21413-22.
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Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Mol Cell. 2014 Feb 20; 53(4):534-48.
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PDP-1 links the TGF-ß and IIS pathways to regulate longevity, development, and metabolism. PLoS Genet. 2011 Apr; 7(4):e1001377.