Platelet Activating Factor

"Platelet Activating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.

Descriptor ID

D010972

MeSH Number(s)

D02.033.100.291.211.500

D02.092.063.291.211.500

D02.092.877.883.333.710

D02.675.276.232.710

D10.570.755.375.760.400.985.910

D23.119.865

D23.469.050.600

Concept/Terms

Platelet Activating Factor

Below are MeSH descriptors whose meaning is more general than "Platelet Activating Factor".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Alcohols [D02.033]
Amino Alcohols [D02.033.100]
Ethanolamines [D02.033.100.291]
Choline [D02.033.100.291.211]
Platelet Activating Factor [D02.033.100.291.211.500]
Amines [D02.092]
Amino Alcohols [D02.092.063]
Ethanolamines [D02.092.063.291]
Choline [D02.092.063.291.211]
Platelet Activating Factor [D02.092.063.291.211.500]
Quaternary Ammonium Compounds [D02.092.877]
Trimethyl Ammonium Compounds [D02.092.877.883]
Choline [D02.092.877.883.333]
Platelet Activating Factor [D02.092.877.883.333.710]
Onium Compounds [D02.675]
Quaternary Ammonium Compounds [D02.675.276]
Choline [D02.675.276.232]
Platelet Activating Factor [D02.675.276.232.710]
Lipids [D10]
Membrane Lipids [D10.570]
Phospholipids [D10.570.755]
Glycerophosphates [D10.570.755.375]
Phosphatidic Acids [D10.570.755.375.760]
Glycerophospholipids [D10.570.755.375.760.400]
Phospholipid Ethers [D10.570.755.375.760.400.985]
Platelet Activating Factor [D10.570.755.375.760.400.985.910]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
Platelet Activating Factor [D23.119.865]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Platelet Activating Factor [D23.469.050.600]

Below are MeSH descriptors whose meaning is related to "Platelet Activating Factor".

Below are MeSH descriptors whose meaning is more specific than "Platelet Activating Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Platelet Activating Factor" by people in Harvard Catalyst Profiles by year, and whether "Platelet Activating Factor" was a major or minor topic of these publication.

Bar chart showing 83 publications over 24 distinct years, with a maximum of 12 publications in 1994

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	10	2	12
1995	8	2	10
1996	4	3	7
1997	2	3	5
1998	1	6	7
1999	0	2	2
2000	2	0	2
2001	1	2	3
2002	1	4	5
2003	4	0	4
2004	1	2	3
2005	2	2	4
2006	1	0	1
2007	0	1	1
2008	1	1	2
2010	1	2	3
2011	0	1	1
2012	1	1	2
2013	1	0	1
2014	0	1	1
2015	1	3	4
2016	0	1	1
2020	0	1	1
2021	0	1	1

Below are the most recent publications written about "Platelet Activating Factor" by people in Profiles.

The Platelet-Activating Factor Receptor's Association with the Outcome of Ovarian Cancer Patients and Its Experimental Inhibition by Rupatadine. Cells. 2021 09 07; 10(9).

View in: PubMed
Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils. J Leukoc Biol. 2021 05; 109(5):915-930.

View in: PubMed
Inositol-C2-PAF acts as a biological response modifier and antagonizes cancer-relevant processes in mammary carcinoma cells. Cell Oncol (Dordr). 2018 Oct; 41(5):505-516.

View in: PubMed
Anti-platelet effects of anti-glaucomatous eye drops: an in vitro study on human platelets. Drug Des Devel Ther. 2017; 11:1267-1272.

View in: PubMed
Anaphylaxis in children. Curr Opin Pediatr. 2016 06; 28(3):294-7.

View in: PubMed
Bacterial exploitation of phosphorylcholine mimicry suppresses inflammation to promote airway infection. J Clin Invest. 2015 Oct 01; 125(10):3878-90.

View in: PubMed
Platelets Play Differential Role During the Initiation and Progression of Autoimmune Neuroinflammation. Circ Res. 2015 Oct 09; 117(9):779-92.

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Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest. 2015 Jul 01; 125(7):2808-24.

View in: PubMed
Platelets in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2015 Jun; 135(6):1407-14; quiz 1415.

View in: PubMed
A platelet-activating factor (PAF) receptor deficiency exacerbates diet-induced obesity but PAF/PAF receptor signaling does not contribute to the development of obesity-induced chronic inflammation. Biochem Pharmacol. 2015 Feb 15; 93(4):482-95.

View in: PubMed

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