"Receptors, KIR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells.
MeSH Number(s)
D12.776.543.750.705.895.500
Concept/Terms
Receptors, KIR- Receptors, KIR
- Killer Inhibitory Receptors
- Inhibitory Receptors, Killer
- Receptors, Killer Inhibitory
- Receptor, p58 NK Cell
- p58 Natural Killer Cell Receptor
- KIR Receptor
- Receptor, KIR
- p58 NK Cell Inhibitory Receptor
- Receptor, Killer Inhibitory
- Killer Inhibitory Receptor
- Inhibitory Receptor, Killer
- Killer Immunoglobulin-Like Receptor
- Immunoglobulin-Like Receptor, Killer
- Killer Immunoglobulin Like Receptor
- Receptor, Killer Immunoglobulin-Like
- Killer Cell Immunoglobulin-Like Receptor
- Killer Cell Immunoglobulin Like Receptor
- KIR Family Receptors
- Family Receptors, KIR
- Receptors, KIR Family
- KIR Receptors
- Killer Immunoglobulin-Like Receptor (KIR) Family of Receptors
- Killer Cell Immunoglobulin-Like Receptors
- Killer Cell Immunoglobulin Like Receptors
- p58 NK Cell Receptor
- p58 NK Cell Receptors
Below are MeSH descriptors whose meaning is more general than "Receptors, KIR".
Below are MeSH descriptors whose meaning is more specific than "Receptors, KIR".
This graph shows the total number of publications written about "Receptors, KIR" by people in Harvard Catalyst Profiles by year, and whether "Receptors, KIR" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1996 | 0 | 2 | 2 |
1997 | 0 | 2 | 2 |
1998 | 0 | 2 | 2 |
1999 | 0 | 4 | 4 |
2001 | 0 | 3 | 3 |
2002 | 0 | 3 | 3 |
2003 | 0 | 2 | 2 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2007 | 1 | 2 | 3 |
2008 | 2 | 0 | 2 |
2009 | 2 | 1 | 3 |
2010 | 2 | 2 | 4 |
2011 | 4 | 3 | 7 |
2012 | 1 | 1 | 2 |
2013 | 4 | 0 | 4 |
2014 | 1 | 2 | 3 |
2015 | 0 | 2 | 2 |
2016 | 4 | 2 | 6 |
2017 | 1 | 1 | 2 |
2019 | 1 | 3 | 4 |
2020 | 1 | 0 | 1 |
2021 | 1 | 1 | 2 |
2022 | 0 | 4 | 4 |
2023 | 0 | 3 | 3 |
2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, KIR" by people in Profiles.
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Systematic evaluation of donor-KIR/recipient-HLA interactions in HLA-matched hematopoietic cell transplantation for AML. Blood Adv. 2024 02 13; 8(3):581-590.
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Associations between KIR/KIR-ligand genotypes and clinical outcome for patients with advanced solid tumors receiving BEMPEG plus nivolumab combination therapy in the PIVOT-02 trial. Cancer Immunol Immunother. 2023 Jul; 72(7):2099-2111.
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Association of Killer Cell Immunoglobulin-like Receptor (KIR) Genes and their HLA Ligands with Susceptibility to Takayasu Arteritis in the Iranian Population. Iran J Allergy Asthma Immunol. 2023 Feb 20; 22(1):25-33.
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KIR/KIR-ligand genotypes and clinical outcomes following chemoimmunotherapy in patients with relapsed or refractory neuroblastoma: a report from the Children's Oncology Group. J Immunother Cancer. 2023 02; 11(2).
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Improved outcomes of single-unit cord blood transplantation for acute myeloid leukemia by killer immunoglobulin-like receptor 2DL1-ligand mismatch. Bone Marrow Transplant. 2022 07; 57(7):1171-1179.
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CD8+ Tregs kill pathogenic cells to avert autoimmunity. Trends Immunol. 2022 06; 43(6):415-416.
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KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19. Science. 2022 04 15; 376(6590):eabi9591.
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Coexistence of HLA and KIR ligand mismatches as a risk factor for viral infection early after cord blood transplantation. Bone Marrow Transplant. 2022 05; 57(5):781-789.
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Decidual NK cells kill Zika virus-infected trophoblasts. Proc Natl Acad Sci U S A. 2021 11 23; 118(47).
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KIR3DL3-HHLA2 is a human immunosuppressive pathway and a therapeutic target. Sci Immunol. 2021 07 09; 6(61).