PQQ Cofactor

"PQQ Cofactor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES.

Descriptor ID

D045542

MeSH Number(s)

D03.438.810.835.661

D08.211.682

Concept/Terms

PQQ Cofactor

Below are MeSH descriptors whose meaning is more general than "PQQ Cofactor".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 2-Ring [D03.438]
Quinolines [D03.438.810]
Quinolones [D03.438.810.835]
PQQ Cofactor [D03.438.810.835.661]
Enzymes and Coenzymes [D08]
Coenzymes [D08.211]
PQQ Cofactor [D08.211.682]

Below are MeSH descriptors whose meaning is related to "PQQ Cofactor".

Below are MeSH descriptors whose meaning is more specific than "PQQ Cofactor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "PQQ Cofactor" by people in Harvard Catalyst Profiles by year, and whether "PQQ Cofactor" was a major or minor topic of these publication.

Bar chart showing 4 publications over 3 distinct years, with a maximum of 2 publications in 1994

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1994	2	2
2000	1	1
2002	1	1

Below are the most recent publications written about "PQQ Cofactor" by people in Profiles.

The essential nutrient pyrroloquinoline quinone may act as a neuroprotectant by suppressing peroxynitrite formation. Eur J Neurosci. 2002 Sep; 16(6):1015-24.

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Novel role for the NMDA receptor redox modulatory site in the pathophysiology of seizures. J Neurosci. 2000 Mar 15; 20(6):2409-17.

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The effects of pyrroloquinoline quinone on heme-regulated eIF-2alpha kinase and eIF-2B activities in eukaryotic protein synthesis. Blood Cells Mol Dis. 1997 Aug; 23(2):177-87.

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The catalysis of redox cycling by pyrroloquinoline quinone (PQQ), PQQ derivatives, and isomers and the specificity of inhibitors. Anal Biochem. 1996 Jul 01; 238(2):145-9.

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DT-diaphorase. Redox potential, steady-state, and rapid reaction studies. J Biol Chem. 1995 Jan 20; 270(3):1198-204.

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Redox-cycling detection of dialyzable pyrroloquinoline quinone and quinoproteins. Methods Enzymol. 1995; 258:140-9.

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The putative essential nutrient pyrroloquinoline quinone is neuroprotective in a rodent model of hypoxic/ischemic brain injury. Neuroscience. 1994 Sep; 62(2):399-406.

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Further evidence that pyrroloquinoline quinone interacts with the N-methyl-D-aspartate receptor redox site in rat cortical neurons in vitro. Neurosci Lett. 1994 Feb 28; 168(1-2):189-92.

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Characterization of the glycine-dependent redox-cycling activity in animal fluids and tissues using specific inhibitors and activators: evidence for presence of PQQ. Biochem Biophys Res Commun. 1993 Oct 15; 196(1):61-8.

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PQQ and electron transport in mammalian systems. Nutr Rev. 1993 Jan; 51(1):26-7.

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Rosenberg, Paul

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