Fanconi Anemia Complementation Group C Protein
"Fanconi Anemia Complementation Group C Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Fanconi anemia complementation group protein that regulates the activities of CYTOCHROME P450 REDUCTASE and GLUTATHIONE S-TRANSFERASE. It is found predominately in the CYTOPLASM, but moves to the CELL NUCLEUS in response to FANCE PROTEIN.
Below are MeSH descriptors whose meaning is more general than "Fanconi Anemia Complementation Group C Protein".
Below are MeSH descriptors whose meaning is more specific than "Fanconi Anemia Complementation Group C Protein".
This graph shows the total number of publications written about "Fanconi Anemia Complementation Group C Protein" by people in Harvard Catalyst Profiles by year, and whether "Fanconi Anemia Complementation Group C Protein" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
Below are the most recent publications written about "Fanconi Anemia Complementation Group C Protein" by people in Profiles.
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Two truncating variants in FANCC and breast cancer risk. Sci Rep. 2019 08 29; 9(1):12524.
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Functional analysis of Fanconi anemia mutations in China. Exp Hematol. 2018 10; 66:32-41.e8.
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Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia. Nat Commun. 2017 11 01; 8(1):1238.
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Fanconi anemia gene editing by the CRISPR/Cas9 system. Hum Gene Ther. 2015 Feb; 26(2):114-26.
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Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells. Cell Stem Cell. 2012 Jul 06; 11(1):36-49.
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Upregulation of Fanconi anemia DNA repair genes in melanoma compared with non-melanoma skin cancer. J Invest Dermatol. 2011 Oct; 131(10):2139-42.
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Fanconi anemia pathway heterogeneity revealed by cisplatin and oxaliplatin treatments. Cancer Lett. 2010 Jun 01; 292(1):73-9.
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Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells. Blood. 2009 May 21; 113(21):5111-20.
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Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J Clin Invest. 2007 May; 117(5):1440-9.
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Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia. Blood. 2003 Jul 01; 102(1):7-16.