Histidine Decarboxylase

"Histidine Decarboxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An enzyme that catalyzes the decarboxylation of histidine to histamine and carbon dioxide. It requires pyridoxal phosphate in animal tissues, but not in microorganisms. EC 4.1.1.22.

Descriptor ID

D006640

MeSH Number(s)

D08.811.520.224.125.300

Concept/Terms

Histidine Decarboxylase

Below are MeSH descriptors whose meaning is more general than "Histidine Decarboxylase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Lyases [D08.811.520]
Carbon-Carbon Lyases [D08.811.520.224]
Carboxy-Lyases [D08.811.520.224.125]
Histidine Decarboxylase [D08.811.520.224.125.300]

Below are MeSH descriptors whose meaning is related to "Histidine Decarboxylase".

Below are MeSH descriptors whose meaning is more specific than "Histidine Decarboxylase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Histidine Decarboxylase" by people in Harvard Catalyst Profiles by year, and whether "Histidine Decarboxylase" was a major or minor topic of these publication.

Bar chart showing 8 publications over 5 distinct years, with a maximum of 2 publications in 2001 and 2010 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	1	2
2004	1	0	1
2010	1	1	2
2014	0	2	2
2015	0	1	1

Below are the most recent publications written about "Histidine Decarboxylase" by people in Profiles.

Identification of histaminergic neurons through histamine 3 receptor-mediated autoinhibition. Neuropharmacology. 2016 07; 106:102-15.

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Damage to histaminergic tuberomammillary neurons and other hypothalamic neurons with traumatic brain injury. Ann Neurol. 2015 Jan; 77(1):177-82.

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Ancient origin of mast cells. Biochem Biophys Res Commun. 2014 Aug 22; 451(2):314-8.

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Histamine synthesis is required for granule maturation in murine mast cells. Eur J Immunol. 2014 Jan; 44(1):204-14.

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Distribution and neurochemical characterization of protein kinase C-theta and -delta in the rodent hypothalamus. Neuroscience. 2010 Nov 10; 170(4):1065-79.

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L-histidine decarboxylase and Tourette's syndrome. N Engl J Med. 2010 May 20; 362(20):1901-8.

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Histamine and orexin in the control of arousal, locomotion, and motivation. J Neurosci. 2010 Feb 24; 30(8):2810-1.

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Molecular biology of histidine decarboxylase and prostaglandin receptors. Proc Jpn Acad Ser B Phys Biol Sci. 2010; 86(8):848-66.

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Orexin/hypocretin and histamine: distinct roles in the control of wakefulness demonstrated using knock-out mouse models. J Neurosci. 2009 Nov 18; 29(46):14423-38.

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Activation of histidine decarboxylase through post-translational cleavage by caspase-9 in a mouse mastocytoma P-815. J Biol Chem. 2007 May 04; 282(18):13438-46.

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