"Genes, myb" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
MeSH Number(s)
G05.360.340.024.340.375.500.791.418
Concept/Terms
v-myb Genes- v-myb Genes
- Gene, v-myb
- Genes, v-myb
- v myb Genes
- v-myb Gene
- myb Oncogene
- Oncogene, myb
- Oncogenes, myb
- myb Oncogenes
- v-myb Oncogenes
- Oncogene, v-myb
- Oncogenes, v-myb
- v myb Oncogenes
- v-myb Oncogene
c-myb Genes- c-myb Genes
- Gene, c-myb
- Genes, c-myb
- c myb Genes
- c-myb Gene
- c-myb Proto-Oncogenes
- Proto-Oncogene, c-myb
- Proto-Oncogenes, c-myb
- c myb Proto Oncogenes
- c-myb Proto-Oncogene
Below are MeSH descriptors whose meaning is more general than "Genes, myb".
Below are MeSH descriptors whose meaning is more specific than "Genes, myb".
This graph shows the total number of publications written about "Genes, myb" by people in Harvard Catalyst Profiles by year, and whether "Genes, myb" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
Below are the most recent publications written about "Genes, myb" by people in Profiles.
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c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells. Cell Rep. 2019 05 21; 27(8):2304-2312.e6.
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APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL. Leukemia. 2017 10; 31(10):2057-2064.
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Performance Testing of RREB1, MYB, and CCND1 Fluorescence In Situ Hybridization in Spindle-Cell and Desmoplastic Melanoma Argues for a Two-Step Test Algorithm. Int J Surg Pathol. 2017 Apr; 25(2):148-157.
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The genetic basis of asymptomatic codon 8 frame-shift (HBB:c25_26delAA) ß(0) -thalassaemia homozygotes. Br J Haematol. 2016 Mar; 172(6):958-65.
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A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression. J Exp Med. 2015 Sep 21; 212(10):1551-69.
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Genomic landscape of adenoid cystic carcinoma of the breast. J Pathol. 2015 Oct; 237(2):179-89.
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Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms. Nat Commun. 2015 Apr 07; 6:6691.
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Novel genetic mutations in a sporadic port-wine stain. JAMA Dermatol. 2014 Dec; 150(12):1336-40.
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Deep penetrating nevus-like borderline tumors: A unique subset of ambiguous melanocytic tumors with malignant potential and normal cytogenetics. Eur J Dermatol. 2014 Sep-Oct; 24(5):594-602.
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MYB immunostaining is a useful ancillary test for distinguishing adenoid cystic carcinoma from pleomorphic adenoma in fine-needle aspiration biopsy specimens. Cancer Cytopathol. 2014 Apr; 122(4):257-65.