Cyclin G1

"Cyclin G1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cyclin G subtype that is constitutively expressed throughout the cell cycle. Cyclin G1 is considered a major transcriptional target of TUMOR SUPPRESSOR PROTEIN P53 and is highly induced in response to DNA damage.

Descriptor ID

D056766

MeSH Number(s)

D12.644.360.262.200.100

D12.776.167.218.200.100

D12.776.476.262.200.100

Concept/Terms

Cyclin G1

Below are MeSH descriptors whose meaning is more general than "Cyclin G1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Cyclins [D12.644.360.262]
Cyclin G [D12.644.360.262.200]
Cyclin G1 [D12.644.360.262.200.100]
Proteins [D12.776]
Cell Cycle Proteins [D12.776.167]
Cyclins [D12.776.167.218]
Cyclin G [D12.776.167.218.200]
Cyclin G1 [D12.776.167.218.200.100]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Cyclins [D12.776.476.262]
Cyclin G [D12.776.476.262.200]
Cyclin G1 [D12.776.476.262.200.100]

Below are MeSH descriptors whose meaning is related to "Cyclin G1".

Below are MeSH descriptors whose meaning is more specific than "Cyclin G1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cyclin G1" by people in Harvard Catalyst Profiles by year, and whether "Cyclin G1" was a major or minor topic of these publication.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 1998 and 2001 and 2012 and 2017 and 2019 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2001	0	1	1
2012	1	0	1
2017	1	0	1
2019	1	0	1
2022	0	1	1

Below are the most recent publications written about "Cyclin G1" by people in Profiles.

Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation. J Clin Invest. 2022 12 01; 132(23).

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Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair. Sci Transl Med. 2019 01 23; 11(476).

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G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells. Nat Cell Biol. 2017 03; 19(3):177-188.

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Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation. J Biol Chem. 2013 Feb 15; 288(7):4704-14.

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Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. Alcohol Clin Exp Res. 2013 Apr; 37(4):599-608.

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Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):12042-7.

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Temporal and spatial control of HGC1 expression results in Hgc1 localization to the apical cells of hyphae in Candida albicans. Eukaryot Cell. 2007 Feb; 6(2):253-61.

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The negative role of cyclin G in ATM-dependent p53 activation. Oncogene. 2004 Jul 08; 23(31):5405-8.

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Borna disease virus phosphoprotein represses p53-mediated transcriptional activity by interference with HMGB1. J Virol. 2003 Nov; 77(22):12243-51.

View in: PubMed
Modulation of p53 and p73 levels by cyclin G: implication of a negative feedback regulation. Oncogene. 2003 Mar 20; 22(11):1678-87.

View in: PubMed

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