"Patch-Clamp Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
Concept/Terms
Patch-Clamp Techniques- Patch-Clamp Techniques
- Patch Clamp Techniques
- Patch-Clamp Technique
- Technique, Patch-Clamp
- Techniques, Patch-Clamp
- Patch-Clamp Technics
- Patch Clamp Technics
- Patch-Clamp Technic
- Technic, Patch-Clamp
- Technics, Patch-Clamp
Whole-Cell Recording- Whole-Cell Recording
- Recording, Whole-Cell
- Recordings, Whole-Cell
- Whole Cell Recording
- Whole-Cell Recordings
Voltage-Clamp Techniques- Voltage-Clamp Techniques
- Technique, Voltage-Clamp
- Techniques, Voltage-Clamp
- Voltage Clamp Techniques
- Voltage-Clamp Technique
- Voltage-Clamp Technics
- Technic, Voltage-Clamp
- Technics, Voltage-Clamp
- Voltage Clamp Technics
- Voltage-Clamp Technic
Below are MeSH descriptors whose meaning is more general than "Patch-Clamp Techniques".
Below are MeSH descriptors whose meaning is more specific than "Patch-Clamp Techniques".
This graph shows the total number of publications written about "Patch-Clamp Techniques" by people in Harvard Catalyst Profiles by year, and whether "Patch-Clamp Techniques" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
1995 | 0 | 13 | 13 |
1996 | 0 | 17 | 17 |
1997 | 0 | 21 | 21 |
1998 | 0 | 18 | 18 |
1999 | 0 | 28 | 28 |
2000 | 0 | 17 | 17 |
2001 | 0 | 25 | 25 |
2002 | 1 | 29 | 30 |
2003 | 0 | 33 | 33 |
2004 | 0 | 36 | 36 |
2005 | 2 | 36 | 38 |
2006 | 1 | 41 | 42 |
2007 | 1 | 36 | 37 |
2008 | 0 | 50 | 50 |
2009 | 1 | 43 | 44 |
2010 | 0 | 35 | 35 |
2011 | 0 | 37 | 37 |
2012 | 2 | 37 | 39 |
2013 | 2 | 32 | 34 |
2014 | 2 | 34 | 36 |
2015 | 1 | 26 | 27 |
2016 | 1 | 27 | 28 |
2017 | 1 | 19 | 20 |
2018 | 1 | 21 | 22 |
2019 | 0 | 15 | 15 |
2020 | 1 | 7 | 8 |
2021 | 2 | 10 | 12 |
2022 | 0 | 2 | 2 |
2023 | 0 | 3 | 3 |
Below are the most recent publications written about "Patch-Clamp Techniques" by people in Profiles.
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Layer 1 neocortex: Gating and integrating multidimensional signals. Neuron. 2024 Jan 17; 112(2):184-200.
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A cell-type-specific error-correction signal in the posterior parietal cortex. Nature. 2023 Aug; 620(7973):366-373.
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A Ventromedial Prefrontal-to-Lateral Entorhinal Cortex Pathway Modulates the Gain of Behavioral Responding During Threat. Biol Psychiatry. 2023 08 01; 94(3):239-248.
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The developmental changes in intrinsic and synaptic properties of prefrontal neurons enhance local network activity from the second to the third postnatal weeks in mice. Cereb Cortex. 2022 08 22; 32(17):3633-3650.
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Perinatal Opioid Exposure Results in Persistent Hypoconnectivity of Excitatory Circuits and Reduced Activity Correlations in Mouse Primary Auditory Cortex. J Neurosci. 2022 04 27; 42(17):3676-3687.
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Contributions of NaV1.8 and NaV1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons. Sci Rep. 2021 12 20; 11(1):24283.
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CNNM proteins selectively bind to the TRPM7 channel to stimulate divalent cation entry into cells. PLoS Biol. 2021 12; 19(12):e3001496.
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a2d-2 is required for depolarization-induced suppression of excitation in Purkinje cells. J Physiol. 2022 01; 600(1):111-122.
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Retina-attached slice recording reveals light-triggered tonic GABA signaling in suprachiasmatic nucleus. Mol Brain. 2021 11 27; 14(1):171.
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Graded heterogeneity of metabotropic signaling underlies a continuum of cell-intrinsic temporal responses in unipolar brush cells. Nat Commun. 2021 10 07; 12(1):5491.