Nerve Fibers, Unmyelinated
"Nerve Fibers, Unmyelinated" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the unmyelinated nerve fibers are small. The axons to SCHWANN CELLS ratio is greater in the unmyelinated nerve fibers than that in the myelinated fiber (NERVE FIBERS, MYELINATED) which is 1:1. Usually several axons are surrounded by a single Schwann cell in the unmyelinated nerve fibers. Therefore, each unmyelinated fiber is not completely covered by the MYELIN SHEATH formed by the Schwann cell. Unmyelinated nerve fibers conduct impulses at low velocities. They represent the majority of peripheral sensory and autonomic fibers. They are also found in the spinal cord and brain.
Below are MeSH descriptors whose meaning is more general than "Nerve Fibers, Unmyelinated".
Below are MeSH descriptors whose meaning is more specific than "Nerve Fibers, Unmyelinated".
This graph shows the total number of publications written about "Nerve Fibers, Unmyelinated" by people in Harvard Catalyst Profiles by year, and whether "Nerve Fibers, Unmyelinated" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 2 | 3 |
2003 | 2 | 2 | 4 |
2004 | 1 | 1 | 2 |
2006 | 2 | 2 | 4 |
2007 | 2 | 2 | 4 |
2008 | 1 | 3 | 4 |
2009 | 0 | 2 | 2 |
2010 | 3 | 3 | 6 |
2012 | 4 | 1 | 5 |
2013 | 3 | 4 | 7 |
2014 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 2 | 2 | 4 |
2018 | 1 | 0 | 1 |
2019 | 1 | 1 | 2 |
2020 | 1 | 2 | 3 |
2021 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Nerve Fibers, Unmyelinated" by people in Profiles.
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Atogepant - an orally-administered CGRP antagonist - attenuates activation of meningeal nociceptors by CSD. Cephalalgia. 2022 08; 42(9):933-943.
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Slow development of bladder malfunction parallels spinal cord fiber sprouting and interneurons' loss after spinal cord transection. Exp Neurol. 2022 02; 348:113937.
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Combined onabotulinumtoxinA/atogepant treatment blocks activation/sensitization of high-threshold and wide-dynamic range neurons. Cephalalgia. 2021 01; 41(1):17-32.
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Idiopathic distal sensory polyneuropathy: ACTTION diagnostic criteria. Neurology. 2020 12 01; 95(22):1005-1014.
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Activation of Peripheral and Central Trigeminovascular Neurons by Seizure: Implications for Ictal and Postictal Headache. J Neurosci. 2020 07 01; 40(27):5314-5326.
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Nuclear Factor I/A Controls A-fiber Nociceptor Development. Neurosci Bull. 2020 Jul; 36(7):685-695.
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Stain-Free Resolution of Unmyelinated Axons in Transgenic Mice Using Fluorescence Microscopy. J Neuropathol Exp Neurol. 2019 12 01; 78(12):1178-1180.
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Exploring the effects of extracranial injections of botulinum toxin type A on prolonged intracranial meningeal nociceptors responses to cortical spreading depression in female rats. Cephalalgia. 2019 10; 39(11):1358-1365.
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Non-Peptidergic Nociceptive Neurons Are Essential for Mechanical Inflammatory Hypersensitivity in Mice. Mol Neurobiol. 2019 Aug; 56(8):5715-5728.
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Thermal A-d Nociceptors, Identified by Transcriptomics, Express Higher Levels of Anesthesia-Sensitive Receptors Than Thermal C-Fibers and Are More Suppressible by Low-Dose Isoflurane. Anesth Analg. 2018 07; 127(1):263-266.