gamma-Crystallins

"gamma-Crystallins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subclass of crystallins that found in the lens (LENS, CRYSTALLINE) of VERTEBRATES. Gamma-crystallins are similar in structure to BETA-CRYSTALLINS in that they both form into a Greek key-like structure. They are composed of monomeric subunits.

Descriptor ID

D038222

MeSH Number(s)

D12.776.306.366.850

Concept/Terms

gamma-Crystallins

Below are MeSH descriptors whose meaning is more general than "gamma-Crystallins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Eye Proteins [D12.776.306]
Crystallins [D12.776.306.366]
gamma-Crystallins [D12.776.306.366.850]

Below are MeSH descriptors whose meaning is related to "gamma-Crystallins".

Below are MeSH descriptors whose meaning is more specific than "gamma-Crystallins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "gamma-Crystallins" by people in Harvard Catalyst Profiles by year, and whether "gamma-Crystallins" was a major or minor topic of these publication.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 2006 and 2007 and 2009 and 2011 and 2012 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	1	0	1
2007	0	1	1
2009	1	0	1
2011	1	0	1
2012	1	0	1
2018	0	1	1

Below are the most recent publications written about "gamma-Crystallins" by people in Profiles.

Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma. Sci Rep. 2018 02 15; 8(1):3124.

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Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells. Cell Res. 2015 Jan; 25(1):67-79.

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The tumor suppressor, p53 regulates the ?A-crystallin gene during mouse lens development. Curr Mol Med. 2014; 14(9):1197-204.

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Novel crystallin gamma B mutations in a Kuwaiti family with autosomal dominant congenital cataracts reveal genetic and clinical heterogeneity. Mol Vis. 2012; 18:2931-6.

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Crystalline cataract caused by a heterozygous missense mutation in ?D-crystallin (CRYGD). Mol Vis. 2011; 17:3333-8.

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Phase behavior of mixtures of human lens proteins Gamma D and Beta B1. Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30):13282-7.

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Founder heterozygous P23T CRYGD mutation associated with cerulean (and coralliform) cataract in 2 Saudi families. Mol Vis. 2009 Jul 24; 15:1407-11.

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Altered phase diagram due to a single point mutation in human gammaD-crystallin. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):16856-61.

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Pax6 is misexpressed in Sox1 null lens fiber cells. Gene Expr Patterns. 2007 Apr; 7(5):606-13.

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AlphaA-crystallin expression prevents gamma-crystallin insolubility and cataract formation in the zebrafish cloche mutant lens. Development. 2006 Jul; 133(13):2585-93.

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