D053837PhysiologyG02.111.087.217G02.149.115.217G05.355.14243580.946642DNA Cleavagecatalyst:eCommonsLogineCommons LoginFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson2.423730.023249143research area of0.9031120.078364974subject area forMedicinePathologyPediatricsInfectious DiseaseBrigham and Women's HospitalBoston Children's HospitalMassachusetts General HospitalJKJ2JaeJoungJae Keith Joung, M.D.,Ph.D.42.37730000000000-71.0525000000000021868Joung, JaeProfessor of Pathology (on leave)33616095Etson CM, Todorov P, Shatery Nejad N, Shrestha N, Walt DRJournal of visualized experiments : JoVESingle-Molecule Dwell-Time Analysis of Restriction Endonuclease-Mediated DNA Cleavage. J Vis Exp. 2021 02 07; (168).J Vis Exp2021-02-07T00:00:002021Single-Molecule Dwell-Time Analysis of Restriction Endonuclease-Mediated DNA Cleavage.36203014Christie KA, Guo JA, Silverstein RA, Doll RM, Mabuchi M, Stutzman HE, Lin J, Ma L, Walton RT, Pinello L, Robb GB, Kleinstiver BPNature biotechnologyPrecise DNA cleavage using CRISPR-SpRYgests. Nat Biotechnol. 2023 Mar; 41(3):409-416.Nat Biotechnol2022-10-06T00:00:002022Precise DNA cleavage using CRISPR-SpRYgests.vit949VinayakTumuluriVinayak Sadasivam Tumuluri, Ph.D.211943Tumuluri, VinayakResearch Fellow in Medicine33533920Tumuluri VS, Rajgor V, Xu SY, Chouhan OP, Saikrishnan KNucleic acids researchMechanism of DNA cleavage by the endonuclease SauUSI: a major barrier to horizontal gene transfer and antibiotic resistance in Staphylococcus aureus. Nucleic Acids Res. 2021 02 26; 49(4):2161-2178.Nucleic Acids Res2021-02-26T00:00:002021Mechanism of DNA cleavage by the endonuclease SauUSI: a major barrier to horizontal gene transfer and antibiotic resistance in Staphylococcus aureus.32527834Liu Y, Zou RS, He S, Nihongaki Y, Li X, Razavi S, Wu B, Ha TScience (New York, N.Y.)Very fast CRISPR on demand. Science. 2020 06 12; 368(6496):1265-1269.Science2020-06-12T00:00:002020Very fast CRISPR on demand.tah111TaekjipHaTaekjip Ha, Ph.D.216282Ha, TaekjipGeorge D. Yancopoulos, MD, PhD Professor of Pediatrics in honor of Frederick W. Alt, PhD34767923Okafor IC, Choi J, Ha TMethods (San Diego, Calif.)Single molecule methods for studying CRISPR Cas9-induced DNA unwinding. Methods. 2022 Aug; 204:319-326.Methods2021-11-10T00:00:002021Single molecule methods for studying CRISPR Cas9-induced DNA unwinding.true1Hansjörg Wyss Professor of Biologically Inspired Engineering, Professor of PathologyHansjörg Wyss Professor of Biologically Inspired Engineering, Professor of Pathologytrue1Professor of Pathology (on leave)Professor of Pathology (on leave)true1Associate Professor of PathologyAssociate Professor of Pathologytrue1Research Fellow in MedicineResearch Fellow in Medicinetrue1George D. Yancopoulos, MD, PhD Professor of Pediatrics in honor of Frederick W. Alt, PhDGeorge D. Yancopoulos, MD, PhD Professor of Pediatrics in honor of Frederick W. Alt, PhDBPK12BenjaminKleinstiverBenjamin P Kleinstiver, Ph.D.122432Kleinstiver, BenjaminAssociate Professor of PathologyCellular and Molecular Medicine1Associate Professor6Fellow or Post Doc0Full ProfessorDRW17DavidWaltDavid Walt, Ph.D.160170Walt, DavidHansjörg Wyss Professor of Biologically Inspired Engineering, Professor of Pathology