Aphasia, Primary Progressive
"Aphasia, Primary Progressive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)
MeSH Number(s)
C10.228.140.380.132
C10.597.606.150.500.800.100.155
C23.888.592.604.150.500.800.100.155
F03.087.400.125
Concept/Terms
Aphasia, Primary Progressive- Aphasia, Primary Progressive
- Aphasias, Primary Progressive
- Primary Progressive Aphasia
- Primary Progressive Aphasias
- Progressive Aphasia, Primary
- Progressive Aphasias, Primary
- Mesulam's Syndrome
- Syndrome, Mesulam's
- Mesulam Syndrome
- Syndrome, Mesulam
Below are MeSH descriptors whose meaning is more general than "Aphasia, Primary Progressive".
Below are MeSH descriptors whose meaning is more specific than "Aphasia, Primary Progressive".
This graph shows the total number of publications written about "Aphasia, Primary Progressive" by people in Harvard Catalyst Profiles by year, and whether "Aphasia, Primary Progressive" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2007 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2010 | 3 | 0 | 3 |
2011 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2017 | 2 | 2 | 4 |
2018 | 3 | 0 | 3 |
2019 | 6 | 0 | 6 |
2020 | 4 | 0 | 4 |
2021 | 4 | 0 | 4 |
2022 | 6 | 1 | 7 |
2023 | 4 | 0 | 4 |
2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Aphasia, Primary Progressive" by people in Profiles.
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Neural basis of speech and grammar symptoms in non-fluent variant primary progressive aphasia spectrum. Brain. 2024 02 01; 147(2):607-626.
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[18F]PI-2620 Binding Patterns in Patients with Suspected Alzheimer Disease and Frontotemporal Lobar Degeneration. J Nucl Med. 2023 12 01; 64(12):1980-1989.
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Assessing processing speed and its neural correlates in the three variants of primary progressive aphasia with a non-verbal tablet-based task. Cortex. 2024 Feb; 171:165-177.
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Expressive Prosody in Patients With Focal Anterior Temporal Neurodegeneration. Neurology. 2023 08 22; 101(8):e825-e835.
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Network anatomy in logopenic variant of primary progressive aphasia. Hum Brain Mapp. 2023 08 01; 44(11):4390-4406.
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Automated Analysis of Written Language in the Three Variants of Primary Progressive Aphasia. Alzheimers Dement. 2022 Dec; 18 Suppl 2:e067739.
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Acoustic and Kinematic Assessment of Motor Speech Impairment in Patients With Suspected Four-Repeat Tauopathies. J Speech Lang Hear Res. 2022 11 17; 65(11):4112-4132.
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Association of Regional Cortical Network Atrophy With Progression to Dementia in Patients With Primary Progressive Aphasia. Neurology. 2023 01 17; 100(3):e286-e296.
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A syntax-lexicon trade-off in language production. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2120203119.
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Dysgraphia Phenotypes in Native Chinese Speakers With Primary Progressive Aphasia. Neurology. 2022 05 31; 98(22):e2245-e2257.