"Calcimycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
Concept/Terms
A-23187- A-23187
- A 23187
- Antibiotic A23187
- A23187, Antibiotic
- A23187
Below are MeSH descriptors whose meaning is more general than "Calcimycin".
Below are MeSH descriptors whose meaning is more specific than "Calcimycin".
This graph shows the total number of publications written about "Calcimycin" by people in Harvard Catalyst Profiles by year, and whether "Calcimycin" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 8 | 9 |
| 1995 | 0 | 6 | 6 |
| 1996 | 0 | 5 | 5 |
| 1997 | 0 | 7 | 7 |
| 1998 | 0 | 3 | 3 |
| 1999 | 1 | 2 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 4 | 4 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Calcimycin" by people in Profiles.
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The erythroid K-Cl cotransport inhibitor [(dihydroindenyl)oxy]acetic acid blocks erythroid Ca2+-activated K+ channel KCNN4. Am J Physiol Cell Physiol. 2022 09 01; 323(3):C694-C705.
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The role of propofol hydroxyl group in 5-lipoxygenase recognition. Biochem Biophys Res Commun. 2020 05 14; 525(4):909-914.
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Superoxide generation from nNOS splice variants and its potential involvement in redox signal regulation. Biochem J. 2017 03 15; 474(7):1149-1162.
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Endothelial AMPK activation induces mitochondrial biogenesis and stress adaptation via eNOS-dependent mTORC1 signaling. Nitric Oxide. 2016 05 01; 55-56:45-53.
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Brain synaptosomes harbor more than one cytoplasmic system of protein synthesis. J Neurosci Res. 2014 Nov; 92(11):1573-80.
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Increased calcium influx triggers and accelerates cortical spreading depression in vivo in male adult rats. Neurosci Lett. 2014 Jan 13; 558:87-90.
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Lactadherin inhibits secretory phospholipase A2 activity on pre-apoptotic leukemia cells. PLoS One. 2013; 8(10):e77143.
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Endothelin-1 receptor antagonists regulate cell surface-associated protein disulfide isomerase in sickle cell disease. FASEB J. 2013 Nov; 27(11):4619-29.
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Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis. Cell Calcium. 2013 Sep; 54(3):186-92.
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The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis. Biochim Biophys Acta. 2013 Jul; 1833(7):1745-54.