"Trypanosomiasis, African" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces "African sleeping sickness." Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
Concept/Terms
Trypanosomiasis, African- Trypanosomiasis, African
- African Trypanosomiases
- Trypanosomiases, African
- African Sleeping Sickness
- African Sleeping Sicknesses
- Sickness, African Sleeping
- Sicknesses, African Sleeping
- Sleeping Sickness, African
- Sleeping Sicknesses, African
- African Trypanosomiasis
Below are MeSH descriptors whose meaning is more general than "Trypanosomiasis, African".
Below are MeSH descriptors whose meaning is more specific than "Trypanosomiasis, African".
This graph shows the total number of publications written about "Trypanosomiasis, African" by people in Harvard Catalyst Profiles by year, and whether "Trypanosomiasis, African" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1999 | 1 | 0 | 1 |
2002 | 1 | 0 | 1 |
2005 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2010 | 0 | 2 | 2 |
2013 | 0 | 1 | 1 |
2014 | 5 | 1 | 6 |
2016 | 0 | 2 | 2 |
2017 | 1 | 0 | 1 |
2018 | 1 | 1 | 2 |
2020 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
Below are the most recent publications written about "Trypanosomiasis, African" by people in Profiles.
-
Identification of a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1. Nat Commun. 2023 07 20; 14(1):4390.
-
The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3. mBio. 2021 12 21; 12(6):e0260221.
-
Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis. PLoS Pathog. 2021 11; 17(11):e1010060.
-
Optimization of 2-(1H-imidazo-2-yl)piperazines series of Trypanosoma brucei growth inhibitors as potential treatment for the second stage of HAT. Bioorg Med Chem Lett. 2020 06 15; 30(12):127207.
-
A Major Step towards Defining the Elusive Stumpy Inducing Factor in Trypanosoma brucei. Trends Parasitol. 2019 01; 35(1):6-8.
-
Phe71 in Type III Trypanosomal Protein Arginine Methyltransferase 7 (TbPRMT7) Restricts the Enzyme to Monomethylation. Biochemistry. 2018 02 27; 57(8):1349-1359.
-
A Brief History of APOL1: A Gene Evolving. Semin Nephrol. 2017 11; 37(6):508-513.
-
The proteome and transcriptome of the infectious metacyclic form of Trypanosoma brucei define quiescent cells primed for mammalian invasion. Mol Microbiol. 2017 Oct; 106(1):74-92.
-
9-(2'-Deoxy-2'-Fluoro-ß-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance. Antimicrob Agents Chemother. 2017 06; 61(6).
-
Adipose Tissue: A Safe Haven for Parasites? Trends Parasitol. 2017 04; 33(4):276-284.