Adaptor Protein Complex 1

"Adaptor Protein Complex 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A clathrin adaptor protein complex primarily involved in clathrin-related transport at the TRANS-GOLGI NETWORK.

Descriptor ID

D033961

MeSH Number(s)

D12.776.543.990.150.100

Concept/Terms

Adaptor Protein Complex 1

Below are MeSH descriptors whose meaning is more general than "Adaptor Protein Complex 1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Vesicular Transport Proteins [D12.776.543.990]
Adaptor Proteins, Vesicular Transport [D12.776.543.990.150]
Adaptor Protein Complex 1 [D12.776.543.990.150.100]

Below are MeSH descriptors whose meaning is related to "Adaptor Protein Complex 1".

Below are MeSH descriptors whose meaning is more specific than "Adaptor Protein Complex 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adaptor Protein Complex 1" by people in Harvard Catalyst Profiles by year, and whether "Adaptor Protein Complex 1" was a major or minor topic of these publication.

Bar chart showing 15 publications over 11 distinct years, with a maximum of 2 publications in 1997 and 2010 and 2012 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1997	1	1	2
2003	1	0	1
2004	1	0	1
2009	1	0	1
2010	2	0	2
2011	0	1	1
2012	2	0	2
2019	1	1	2
2021	1	0	1
2023	0	1	1

Below are the most recent publications written about "Adaptor Protein Complex 1" by people in Profiles.

Proteome-Wide Discovery of Cortical Proteins That May Provide Motor Resilience to Offset the Negative Effects of Pathologies in Older Adults. J Gerontol A Biol Sci Med Sci. 2023 03 01; 78(3):494-503.

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De novo and bi-allelic variants in AP1G1 cause neurodevelopmental disorder with developmental delay, intellectual disability, and epilepsy. Am J Hum Genet. 2021 07 01; 108(7):1330-1341.

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Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells. Nat Microbiol. 2020 01; 5(1):181-191.

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Homozygous Loss-of-Function Mutations in AP1B1, Encoding Beta-1 Subunit of Adaptor-Related Protein Complex 1, Cause MEDNIK-like Syndrome. Am J Hum Genet. 2019 11 07; 105(5):1016-1022.

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Dynamics of intracellular clathrin/AP1- and clathrin/AP3-containing carriers. Cell Rep. 2012 Nov 29; 2(5):1111-9.

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Clathrin and AP-1 regulate apical polarity and lumen formation during C. elegans tubulogenesis. Development. 2012 Jun; 139(11):2071-83.

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Recruitment of cellular clathrin to viral factories and disruption of clathrin-dependent trafficking. Traffic. 2011 Sep; 12(9):1179-95.

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AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene. Int J Cancer. 2012 Mar 01; 130(5):1011-20.

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Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. Nat Cell Biol. 2010 Apr; 12(4):330-40.

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Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2556-61.

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