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Immunoglobulin Joining Region

"Immunoglobulin Joining Region" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
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A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.


publications
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This graph shows the total number of publications written about "Immunoglobulin Joining Region" by people in Harvard Catalyst Profiles by year, and whether "Immunoglobulin Joining Region" was a major or minor topic of these publication.
Bar chart showing 18 publications over 11 distinct years, with a maximum of 3 publications in 1998 and 2004
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.