Harvard Catalyst Profiles

An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.

Below are MeSH descriptors whose meaning is more general than "Lupus Coagulation Inhibitor".

Below are MeSH descriptors whose meaning is related to "Lupus Coagulation Inhibitor".

Below are MeSH descriptors whose meaning is more specific than "Lupus Coagulation Inhibitor".