Leukemia, Megakaryoblastic, Acute
"Leukemia, Megakaryoblastic, Acute" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acute myeloid leukemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. MYELOFIBROSIS or increased bone marrow RETICULIN is common.
Concept/Terms
Leukemia, Megakaryoblastic, Acute- Leukemia, Megakaryoblastic, Acute
- Myeloid Leukemia, Acute, M7
- Megakaryocytic Leukemia, Acute
- Acute Megakaryocytic Leukemia
- Acute Megakaryocytic Leukemias
- Leukemia, Acute Megakaryocytic
- Leukemias, Acute Megakaryocytic
- Megakaryocytic Leukemias, Acute
- Megakaryocytic Leukemia
- Megakaryoblastic Leukemia, Acute
- Acute Megakaryoblastic Leukemia
- Acute Megakaryoblastic Leukemias
- Leukemia, Acute Megakaryoblastic
- Leukemias, Acute Megakaryoblastic
- Megakaryoblastic Leukemias, Acute
- Leukemia, Megakaryocytic
- Leukemias, Megakaryocytic
- Megakaryocytic Leukemias
- Leukemia, Myeloid, Acute, M7
- Leukemia, Megakaryocytic, Acute
Below are MeSH descriptors whose meaning is more general than "Leukemia, Megakaryoblastic, Acute".
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Megakaryoblastic, Acute".
This graph shows the total number of publications written about "Leukemia, Megakaryoblastic, Acute" by people in Harvard Catalyst Profiles by year, and whether "Leukemia, Megakaryoblastic, Acute" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 1 | 2 |
1995 | 0 | 1 | 1 |
1996 | 1 | 2 | 3 |
1998 | 0 | 1 | 1 |
1999 | 1 | 0 | 1 |
2000 | 1 | 1 | 2 |
2002 | 1 | 0 | 1 |
2003 | 0 | 1 | 1 |
2005 | 1 | 1 | 2 |
2006 | 3 | 0 | 3 |
2009 | 1 | 0 | 1 |
2010 | 2 | 1 | 3 |
2011 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2017 | 2 | 0 | 2 |
2018 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
Below are the most recent publications written about "Leukemia, Megakaryoblastic, Acute" by people in Profiles.
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Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia. Blood. 2023 03 30; 141(13):1610-1625.
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Germline GATA1s-generating mutations predispose to leukemia with acquired trisomy 21 and Down syndrome-like phenotype. Blood. 2022 05 26; 139(21):3159-3165.
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Leukemia Risk in a Cohort of 3.9 Million Children with and without Down Syndrome. J Pediatr. 2021 Jul; 234:172-180.e3.
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Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia. Pediatr Blood Cancer. 2019 08; 66(8):e27785.
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Outcome of Childhood Acute Megakaryoblastic Leukemia: Children's Cancer Hospital Egypt 57357 Experience. Clin Lymphoma Myeloma Leuk. 2019 03; 19(3):e142-e152.
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Chemokine levels predict progressive liver disease in Down syndrome patients with transient abnormal myelopoiesis. Pediatr Neonatol. 2019 08; 60(4):382-388.
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GATA1 Is a Sensitive and Specific Nuclear Marker for Erythroid and Megakaryocytic Lineages. Am J Clin Pathol. 2017 Apr 01; 147(4):420-426.
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ETO2-GLIS2: A Chimeric Transcription Factor Drives Leukemogenesis through a Neomorphic Transcription Network. Cancer Cell. 2017 03 13; 31(3):307-308.
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Acute Erythroleukemias, Acute Megakaryoblastic Leukemias, and Reactive Mimics: A Guide to a Number of Perplexing Entities. Am J Clin Pathol. 2015 Jul; 144(1):44-60.
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Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Cell. 2012 Aug 03; 150(3):575-89.