Plasminogen

"Plasminogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Precursor of plasmin (FIBRINOLYSIN). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.

Descriptor ID

D010958

MeSH Number(s)

D08.622.610

D12.776.124.790.223.580

D12.776.377.715.182.580

Concept/Terms

Plasminogen

Glu-Plasminogen

Below are MeSH descriptors whose meaning is more general than "Plasminogen".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzyme Precursors [D08.622]
Plasminogen [D08.622.610]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Serum Globulins [D12.776.124.790]
Beta-Globulins [D12.776.124.790.223]
Plasminogen [D12.776.124.790.223.580]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Beta-Globulins [D12.776.377.715.182]
Plasminogen [D12.776.377.715.182.580]

Below are MeSH descriptors whose meaning is related to "Plasminogen".

Below are MeSH descriptors whose meaning is more specific than "Plasminogen".

Plasminogen
Angiostatins

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Plasminogen" by people in Harvard Catalyst Profiles by year, and whether "Plasminogen" was a major or minor topic of these publication.

Bar chart showing 81 publications over 23 distinct years, with a maximum of 11 publications in 1998

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	4	3	7
1995	2	2	4
1996	3	1	4
1997	3	0	3
1998	9	2	11
1999	1	3	4
2000	3	3	6
2001	2	2	4
2002	5	3	8
2003	3	4	7
2004	1	1	2
2005	0	1	1
2006	3	0	3
2007	2	0	2
2008	1	1	2
2009	0	2	2
2011	0	1	1
2012	1	0	1
2013	1	2	3
2016	2	0	2
2017	1	1	2
2019	0	1	1
2022	0	1	1

Below are the most recent publications written about "Plasminogen" by people in Profiles.

Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells. Cancer Sci. 2022 Jun; 113(6):2179-2193.

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Tranexamic acid mediates proinflammatory and anti-inflammatory signaling via complement C5a regulation in a plasminogen activator-dependent manner. J Trauma Acute Care Surg. 2019 01; 86(1):101-107.

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Ixonnexin from Tick Saliva Promotes Fibrinolysis by Interacting with Plasminogen and Tissue-Type Plasminogen Activator, and Prevents Arterial Thrombosis. Sci Rep. 2018 03 19; 8(1):4806.

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Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin. J Trauma Acute Care Surg. 2017 12; 83(6):1053-1061.

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Rare coding variants pinpoint genes that control human hematological traits. PLoS Genet. 2017 Aug; 13(8):e1006925.

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A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis. Am J Hum Genet. 2017 Jan 05; 100(1):64-74.

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Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients. G3 (Bethesda). 2016 07 07; 6(7):2073-9.

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Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma. Eur Respir J. 2016 05; 47(5):1568-71.

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Concentration of fibrin and presence of plasminogen affect proliferation, fibrinolytic activity, and morphology of human fibroblasts and keratinocytes in 3D fibrin constructs. Tissue Eng Part A. 2014 Nov; 20(21-22):2860-9.

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Serum protein profile of Crohn's disease treated with infliximab. J Crohns Colitis. 2013 Nov; 7(10):e461-70.

View in: PubMed

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