"Leukocyte Rolling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Movement of tethered, spherical LEUKOCYTES along the endothelial surface of the microvasculature. The tethering and rolling involves interaction with SELECTINS and other adhesion molecules in both the ENDOTHELIUM and leukocyte. The rolling leukocyte then becomes activated by CHEMOKINES, flattens out, and firmly adheres to the endothelial surface in preparation for transmigration through the interendothelial cell junction. (From Abbas, Cellular and Molecular Immunology, 3rd ed)
Concept/Terms
Leukocyte Rolling- Leukocyte Rolling
- Rolling, Leukocyte
- Leucocyte Rolling
- Rolling, Leucocyte
Below are MeSH descriptors whose meaning is more general than "Leukocyte Rolling".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte Rolling".
This graph shows the total number of publications written about "Leukocyte Rolling" by people in Harvard Catalyst Profiles by year, and whether "Leukocyte Rolling" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 2 | 0 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 2 | 3 | 5 |
| 2006 | 3 | 1 | 4 |
| 2007 | 2 | 1 | 3 |
| 2008 | 2 | 6 | 8 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 3 | 0 | 3 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 2 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
Below are the most recent publications written about "Leukocyte Rolling" by people in Profiles.
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Myeloid Mineralocorticoid Receptor Transcriptionally Regulates P-Selectin Glycoprotein Ligand-1 and Promotes Monocyte Trafficking and Atherosclerosis. Arterioscler Thromb Vasc Biol. 2021 11; 41(11):2740-2755.
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Immunometabolic Endothelial Phenotypes: Integrating Inflammation and Glucose Metabolism. Circ Res. 2021 06 25; 129(1):9-29.
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Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow. Blood. 2017 11 09; 130(19):2101-2110.
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Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease. Nat Genet. 2017 Sep; 49(9):1392-1397.
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Endotoxaemia-augmented murine venous thrombosis is dependent on TLR-4 and ICAM-1, and potentiated by neutropenia. Thromb Haemost. 2017 01 26; 117(2):339-348.
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Extracellular ATP Induces Vascular Inflammation and Atherosclerosis via Purinergic Receptor Y2 in Mice. Arterioscler Thromb Vasc Biol. 2016 08; 36(8):1577-86.
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Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin-Dependent Rolling in the Multistep Leukocyte Adhesion Cascade. Arterioscler Thromb Vasc Biol. 2016 Apr; 36(4):718-27.
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CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo. J Immunol. 2016 Feb 01; 196(3):1305-1316.
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A Short Peptide That Mimics the Binding Domain of TGF-ß1 Presents Potent Anti-Inflammatory Activity. PLoS One. 2015; 10(8):e0136116.
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Metformin modulates human leukocyte/endothelial cell interactions and proinflammatory cytokines in polycystic ovary syndrome patients. Atherosclerosis. 2015 Sep; 242(1):167-73.