Ribosomal Protein S6 Kinases, 90-kDa
"Ribosomal Protein S6 Kinases, 90-kDa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN.
MeSH Number(s)
D08.811.913.696.620.682.700.862.500
D12.644.360.600.500
D12.776.476.600.500
Concept/Terms
Ribosomal Protein S6 Kinases, 90-kDa- Ribosomal Protein S6 Kinases, 90-kDa
- Ribosomal Protein S6 Kinases, 90 kDa
- MAP-Kinase-Activated Protein Kinase 1
- MAP Kinase Activated Protein Kinase 1
- MAPKAP Kinase-1
- MAPKAP Kinase 1
- MAPKAP-K1
- Ribosomal Protein S6 Kinase, 90-kDa
- Ribosomal Protein S6 Kinase, 90 kDa
- p90 Ribosomal S6 Kinase
- p90(rsk)
- pp90(rsk)
- MAP-Kinase-Activated Kinase 1
- MAP Kinase Activated Kinase 1
- MAPKAPK1
Below are MeSH descriptors whose meaning is more general than "Ribosomal Protein S6 Kinases, 90-kDa".
Below are MeSH descriptors whose meaning is more specific than "Ribosomal Protein S6 Kinases, 90-kDa".
This graph shows the total number of publications written about "Ribosomal Protein S6 Kinases, 90-kDa" by people in Harvard Catalyst Profiles by year, and whether "Ribosomal Protein S6 Kinases, 90-kDa" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 2 | 3 |
| 2005 | 6 | 0 | 6 |
| 2008 | 0 | 1 | 1 |
| 2009 | 6 | 1 | 7 |
| 2010 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 3 | 2 | 5 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 3 | 5 |
| 2018 | 0 | 1 | 1 |
| 2020 | 2 | 1 | 3 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Ribosomal Protein S6 Kinases, 90-kDa" by people in Profiles.
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Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
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RSK2 Maintains Adult Estrogen Homeostasis by Inhibiting ERK1/2-Mediated Degradation of Estrogen Receptor Alpha. Cell Rep. 2020 07 21; 32(3):107931.
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mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division. Nat Commun. 2020 06 24; 11(1):3200.
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Dehydration stress alters the mitogen-activated-protein kinase signaling and chaperone stress response in Xenopus laevis. Comp Biochem Physiol B Biochem Mol Biol. 2020 Aug - Sep; 246-247:110461.
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Regioselective Synthesis of a C-4'' Carbamate,C-6'' n-Pr Substituted Cyclitol Analogue of SL0101. Org Lett. 2020 02 21; 22(4):1448-1452.
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Fisetin targets YB-1/RSK axis independent of its effect on ERK signaling: insights from in vitro and in vivo melanoma models. Sci Rep. 2018 10 24; 8(1):15726.
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L1 coupling to ankyrin and the spectrin-actin cytoskeleton modulates ethanol inhibition of L1 adhesion and ethanol teratogenesis. FASEB J. 2018 03; 32(3):1364-1374.
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Mitogen- and stress-activated protein kinase 1 is required for gonadotropin-releasing hormone-mediated activation of gonadotropin a-subunit expression. J Biol Chem. 2017 12 15; 292(50):20720-20731.
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Tribbles 3 regulates protein turnover in mouse skeletal muscle. Biochem Biophys Res Commun. 2017 11 25; 493(3):1236-1242.
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Mitogen- and Stress-Activated Protein Kinase 1 Regulates Status Epilepticus-Evoked Cell Death in the Hippocampus. ASN Neuro. 2017 Sep-Oct; 9(5):1759091417726607.