Ribonuclease H

"Ribonuclease H" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic organisms as well as RETROVIRUSES.

Descriptor ID

D016914

MeSH Number(s)

D08.811.277.352.355.350.700

D08.811.277.352.700.350.700

Concept/Terms

Ribonuclease H

Ribonuclease H, Calf Thymus

Below are MeSH descriptors whose meaning is more general than "Ribonuclease H".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Endonucleases [D08.811.277.352.355]
Endoribonucleases [D08.811.277.352.355.350]
Ribonuclease H [D08.811.277.352.355.350.700]
Ribonucleases [D08.811.277.352.700]
Endoribonucleases [D08.811.277.352.700.350]
Ribonuclease H [D08.811.277.352.700.350.700]

Below are MeSH descriptors whose meaning is related to "Ribonuclease H".

Below are MeSH descriptors whose meaning is more specific than "Ribonuclease H".

Ribonuclease H
Ribonuclease H, Human Immunodeficiency Virus

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ribonuclease H" by people in Harvard Catalyst Profiles by year, and whether "Ribonuclease H" was a major or minor topic of these publication.

Bar chart showing 29 publications over 17 distinct years, with a maximum of 3 publications in 2002 and 2017 and 2018 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	2	2
1995	1	0	1
1996	0	2	2
2002	0	3	3
2005	0	1	1
2010	0	1	1
2011	0	1	1
2012	0	1	1
2014	1	1	2
2015	0	1	1
2016	1	1	2
2017	2	1	3
2018	2	1	3
2019	0	1	1
2020	0	1	1
2021	1	2	3
2022	0	1	1

Below are the most recent publications written about "Ribonuclease H" by people in Profiles.

RB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer. Sci Adv. 2022 02 18; 8(7):eabl9794.

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Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations. Cancer Res. 2021 09 01; 81(17):4499-4513.

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Case Report: Novel Compound Heterozygous RNASEH2B Mutations Cause Aicardi-Goutières Syndrome. Front Immunol. 2021; 12:672952.

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TonEBP recognizes R-loops and initiates m6A RNA methylation for R-loop resolution. Nucleic Acids Res. 2021 01 11; 49(1):269-284.

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Nucleolar RNA polymerase II drives ribosome biogenesis. Nature. 2020 09; 585(7824):298-302.

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RNase H-dependent PCR-enabled T-cell receptor sequencing for highly specific and efficient targeted sequencing of T-cell receptor mRNA for single-cell and repertoire analysis. Nat Protoc. 2019 08; 14(8):2571-2594.

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Stereocontrolled Synthesis of Boranophosphate DNA by an Oxazaphospholidine Approach and Evaluation of Its Properties. J Org Chem. 2019 06 21; 84(12):7971-7983.

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Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes. Cancer Res. 2018 09 15; 78(18):5363-5374.

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RNA-DNA hybrids promote the expansion of Friedreich's ataxia (GAA)n repeats via break-induced replication. Nucleic Acids Res. 2018 04 20; 46(7):3487-3497.

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Artificial cationic oligosaccharides for heteroduplex oligonucleotide-type drugs. Sci Rep. 2018 03 12; 8(1):4323.

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