STAT4 Transcription Factor

"STAT4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important signaling molecule for differentiation in TH1 CELLS.

Descriptor ID

D050797

MeSH Number(s)

D12.644.360.024.342.400

D12.776.157.057.186.400

D12.776.476.024.421.400

D12.776.930.840.400

Concept/Terms

STAT4 Transcription Factor

STAT4b Transcription Factor

STAT4A Transcription Factor

Below are MeSH descriptors whose meaning is more general than "STAT4 Transcription Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
STAT Transcription Factors [D12.644.360.024.342]
STAT4 Transcription Factor [D12.644.360.024.342.400]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
STAT Transcription Factors [D12.776.157.057.186]
STAT4 Transcription Factor [D12.776.157.057.186.400]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
STAT Transcription Factors [D12.776.476.024.421]
STAT4 Transcription Factor [D12.776.476.024.421.400]
Transcription Factors [D12.776.930]
STAT Transcription Factors [D12.776.930.840]
STAT4 Transcription Factor [D12.776.930.840.400]

Below are MeSH descriptors whose meaning is related to "STAT4 Transcription Factor".

Below are MeSH descriptors whose meaning is more specific than "STAT4 Transcription Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "STAT4 Transcription Factor" by people in Harvard Catalyst Profiles by year, and whether "STAT4 Transcription Factor" was a major or minor topic of these publication.

Bar chart showing 66 publications over 24 distinct years, with a maximum of 7 publications in 2000

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
1997	0	3	3
1998	0	4	4
1999	0	6	6
2000	0	7	7
2001	0	6	6
2002	0	3	3
2003	0	4	4
2004	0	2	2
2005	0	2	2
2006	0	1	1
2007	1	3	4
2008	2	1	3
2009	3	0	3
2010	2	2	4
2011	0	2	2
2012	0	2	2
2013	2	1	3
2014	1	0	1
2016	0	1	1
2017	0	1	1
2018	0	1	1
2020	0	1	1

Below are the most recent publications written about "STAT4 Transcription Factor" by people in Profiles.

Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies. Cell Rep. 2020 01 28; 30(4):984-996.e4.

View in: PubMed
Expansion of T follicular helper-T helper 1 like cells through epigenetic regulation by signal transducer and activator of transcription factors. Ann Rheum Dis. 2018 09; 77(9):1354-1361.

View in: PubMed
Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4. Nat Commun. 2018 03 09; 9(1):1014.

View in: PubMed
Paracoccidioidomycosis Associated With a Heterozygous STAT4 Mutation and Impaired IFN-? Immunity. J Infect Dis. 2017 12 19; 216(12):1623-1634.

View in: PubMed
Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators. Immunity. 2017 02 21; 46(2):220-232.

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Interferon-? is increased in the gut of patients with irritable bowel syndrome and modulates serotonin metabolism. Am J Physiol Gastrointest Liver Physiol. 2016 Mar 15; 310(6):G439-47.

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Replication the association of 2q32.2-q32.3 and 14q32.11 with hepatocellular carcinoma. Gene. 2015 Apr 25; 561(1):63-7.

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Androgens alter T-cell immunity by inhibiting T-helper 1 differentiation. Proc Natl Acad Sci U S A. 2014 Jul 08; 111(27):9887-92.

View in: PubMed
Analysis of STAT4 expression in cutaneous T-cell lymphoma (CTCL) patients and patient-derived cell lines. Cell Cycle. 2014; 13(18):2975-82.

View in: PubMed
STAT4: an initiator of meta-inflammation in adipose tissue? Diabetes. 2013 Dec; 62(12):4002-3.

View in: PubMed

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