Receptors, Purinergic P2X2
"Receptors, Purinergic P2X2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension and NEUROPATHIC PAIN. The receptor comprises three P2X2 subunits. The P2X2 subunits also have been found associated with P2X3 RECEPTOR subunits in a heterotrimeric receptor variant.
MeSH Number(s)
D12.776.157.530.400.400.750.200
D12.776.543.550.425.500.600.200
D12.776.543.585.400.500.600.200
D12.776.543.750.720.700.720.500.200
D12.776.543.750.810.720.500.200
Concept/Terms
Receptors, Purinergic P2X2- Receptors, Purinergic P2X2
- P2X2 Receptors, Purinergic
- Purinergic P2X2 Receptors
- Purinergic Receptor P2X, Ligand-Gated Ion Channel, 2
- P2X2 Receptor
- Receptor, P2X2
- P2X2 Purinoceptor
- Purinoceptor, P2X2
- P2X2 Purinoceptors
- Purinoceptors, P2X2
Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2X2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
- Receptors, Purinergic P2X2 [D12.776.157.530.400.400.750.200]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.425]
- Ligand-Gated Ion Channels [D12.776.543.550.425.500]
- Receptors, Purinergic P2X [D12.776.543.550.425.500.600]
- Receptors, Purinergic P2X2 [D12.776.543.550.425.500.600.200]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
- Receptors, Purinergic P2X2 [D12.776.543.585.400.500.600.200]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
- Receptors, Purinergic P2X2 [D12.776.543.750.720.700.720.500.200]
- Receptors, Purinergic [D12.776.543.750.810]
- Receptors, Purinergic P2 [D12.776.543.750.810.720]
- Receptors, Purinergic P2X [D12.776.543.750.810.720.500]
- Receptors, Purinergic P2X2 [D12.776.543.750.810.720.500.200]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2X2".
This graph shows the total number of publications written about "Receptors, Purinergic P2X2" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Purinergic P2X2" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Purinergic P2X2" by people in Profiles.
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Calcium signalling in T cells. Nat Rev Immunol. 2019 03; 19(3):154-169.
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Corneal Neovascularization: A Combined Approach of Bevacizumab and Suramin Showed Increased Antiangiogenic Effect Through Downregulation of BFGF and P2X2. Curr Eye Res. 2018 04; 43(4):466-473.
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A Neural Network Underlying Circadian Entrainment and Photoperiodic Adjustment of Sleep and Activity in Drosophila. J Neurosci. 2016 08 31; 36(35):9084-96.
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Hearing loss caused by a P2RX2 mutation identified in a MELAS family with a coexisting mitochondrial 3243AG mutation. Ann Otol Rhinol Laryngol. 2015 May; 124 Suppl 1:177S-83S.
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Adenosine triphosphate drives head and neck cancer pain through P2X2/3 heterotrimers. Acta Neuropathol Commun. 2014 Jun 05; 2:62.
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Ectodomain movements of an ATP-gated ion channel (P2X2 receptor) probed by disulfide locking. J Biol Chem. 2014 Apr 04; 289(14):9909-17.
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Optical control of trimeric P2X receptors and acid-sensing ion channels. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):521-6.
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Potent and long-lasting inhibition of human P2X2 receptors by copper. Neuropharmacology. 2014 Feb; 77:167-76.
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P2X receptor intermediate activation states have altered nucleotide selectivity. J Neurosci. 2013 Sep 11; 33(37):14801-8.
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Mutation of the ATP-gated P2X(2) receptor leads to progressive hearing loss and increased susceptibility to noise. Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):2228-33.