Succinate Dehydrogenase

"Succinate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.

Descriptor ID

D013385

MeSH Number(s)

D05.500.562.750.249.500

D08.811.600.250.500.750.500

D08.811.600.250.875.249.500

D08.811.682.660.385.500

D08.811.682.660.750

D08.811.682.830.249.500

D12.776.157.427.374.375.909.500

D12.776.331.199.750.500

D12.776.543.277.500.750.500

D12.776.543.277.875.249.500

D12.776.556.579.374.375.141.500

Concept/Terms

Succinate Dehydrogenase

Below are MeSH descriptors whose meaning is more general than "Succinate Dehydrogenase".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Multiprotein Complexes [D05.500]
Multienzyme Complexes [D05.500.562]
Succinate Cytochrome c Oxidoreductase [D05.500.562.750]
Electron Transport Complex II [D05.500.562.750.249]
Succinate Dehydrogenase [D05.500.562.750.249.500]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Multienzyme Complexes [D08.811.600]
Electron Transport Chain Complex Proteins [D08.811.600.250]
Electron-Transferring Flavoproteins [D08.811.600.250.500]
Electron Transport Complex II [D08.811.600.250.500.750]
Succinate Dehydrogenase [D08.811.600.250.500.750.500]
Succinate Cytochrome c Oxidoreductase [D08.811.600.250.875]
Electron Transport Complex II [D08.811.600.250.875.249]
Succinate Dehydrogenase [D08.811.600.250.875.249.500]
Oxidoreductases [D08.811.682]
Oxidoreductases Acting on CH-CH Group Donors [D08.811.682.660]
Electron Transport Complex II [D08.811.682.660.385]
Succinate Dehydrogenase [D08.811.682.660.385.500]
Succinate Dehydrogenase [D08.811.682.660.750]
Succinate Cytochrome c Oxidoreductase [D08.811.682.830]
Electron Transport Complex II [D08.811.682.830.249]
Succinate Dehydrogenase [D08.811.682.830.249.500]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Iron-Binding Proteins [D12.776.157.427]
Nonheme Iron Proteins [D12.776.157.427.374]
Iron-Sulfur Proteins [D12.776.157.427.374.375]
Electron Transport Complex II [D12.776.157.427.374.375.909]
Succinate Dehydrogenase [D12.776.157.427.374.375.909.500]
Flavoproteins [D12.776.331]
Electron-Transferring Flavoproteins [D12.776.331.199]
Electron Transport Complex II [D12.776.331.199.750]
Succinate Dehydrogenase [D12.776.331.199.750.500]
Metalloproteins [D12.776.556]
Iron-Binding Proteins [D12.776.556.579]
Nonheme Iron Proteins [D12.776.556.579.374]
Iron-Sulfur Proteins [D12.776.556.579.374.375]
Electron Transport Complex II [D12.776.556.579.374.375.141]
Succinate Dehydrogenase [D12.776.556.579.374.375.141.500]

Below are MeSH descriptors whose meaning is related to "Succinate Dehydrogenase".

Below are MeSH descriptors whose meaning is more specific than "Succinate Dehydrogenase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Succinate Dehydrogenase" by people in Harvard Catalyst Profiles by year, and whether "Succinate Dehydrogenase" was a major or minor topic of these publication.

Bar chart showing 75 publications over 26 distinct years, with a maximum of 7 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1995	0	1	1
1996	0	2	2
1997	0	1	1
2000	1	1	2
2001	0	1	1
2002	0	2	2
2005	0	1	1
2006	0	1	1
2007	1	0	1
2008	1	1	2
2009	1	4	5
2010	2	2	4
2011	1	2	3
2012	2	0	2
2013	5	2	7
2014	4	2	6
2015	3	2	5
2016	3	2	5
2017	2	4	6
2018	3	2	5
2019	2	2	4
2020	0	2	2
2021	0	2	2
2022	0	2	2
2023	0	2	2

Below are the most recent publications written about "Succinate Dehydrogenase" by people in Profiles.

Frequency of Alternaria Genotypes Resistant to SDHI Fungicides in California Pistachio Orchards Determined by Real-Time PCR. Plant Dis. 2023 May; 107(5):1433-1441.

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Reduced Risk of Corporal Tumors in Patients With Head and Neck Paragangliomas With p.Pro81Leu Mutations. Otolaryngol Head Neck Surg. 2023 09; 169(3):570-576.

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SDHx mutations and temozolomide in malignant pheochromocytoma and paraganglioma. Endocr Relat Cancer. 2022 09 01; 29(9):533-544.

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PDGFRA Immunohistochemistry Predicts PDGFRA Mutations in Gastrointestinal Stromal Tumors. Am J Surg Pathol. 2022 01 01; 46(1):3-10.

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Expanding the clinicopathological spectrum of succinate dehydrogenase-deficient renal cell carcinoma with a focus on variant morphologies: a study of 62 new tumors in 59 patients. Mod Pathol. 2022 06; 35(6):836-849.

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Fumarate is a terminal electron acceptor in the mammalian electron transport chain. Science. 2021 Dec 03; 374(6572):1227-1237.

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Selenium-dependent metabolic reprogramming during inflammation and resolution. J Biol Chem. 2021 Jan-Jun; 296:100410.

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Bilateral Carotid Body Paraganglioma. Acta Med Port. 2021 Feb 01; 34(2):143.

View in: PubMed
Ancestry-specific predisposing germline variants in cancer. Genome Med. 2020 05 29; 12(1):51.

View in: PubMed
Bmal1 integrates mitochondrial metabolism and macrophage activation. Elife. 2020 05 12; 9.

View in: PubMed

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