"HLA-DR4 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An HLA-DR antigen which is associated with HLA-DRB1 CHAINS encoded by DRB1*04 alleles.
MeSH Number(s)
D12.776.395.550.509.400.440.400.040
D12.776.543.550.423.400.440.400.040
D23.050.301.500.400.400.440.400.040
D23.050.301.500.450.400.440.389.937
D23.050.705.552.410.400.440.389.040
D23.050.705.552.450.400.440.389.937
Below are MeSH descriptors whose meaning is more general than "HLA-DR4 Antigen".
Below are MeSH descriptors whose meaning is more specific than "HLA-DR4 Antigen".
This graph shows the total number of publications written about "HLA-DR4 Antigen" by people in Harvard Catalyst Profiles by year, and whether "HLA-DR4 Antigen" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
Below are the most recent publications written about "HLA-DR4 Antigen" by people in Profiles.
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Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors. Diabetes. 2018 08; 67(8):1471-1480.
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Primary Human and Rat ß-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Diabetes. 2017 02; 66(2):460-473.
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Autoantigen BiP-Derived HLA-DR4 Epitopes Differentially Recognized by Effector and Regulatory T Cells in Rheumatoid Arthritis. Arthritis Rheumatol. 2015 May; 67(5):1171-81.
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Autoantibody and human leukocyte antigen profiles in children with autoimmune liver disease and their first-degree relatives. J Pediatr Gastroenterol Nutr. 2014 Apr; 58(4):457-62.
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Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3e cytoplasmic domain. J Exp Med. 2012 Dec 17; 209(13):2423-39.
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Human a-enolase is immunogenic, but not arthritogenic, in HLA-DR4-transgenic mice: comment on the article by Kinloch et al. Arthritis Rheum. 2012 May; 64(5):1689-91; author reply 1691-2.
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Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2r?(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease. Clin Exp Immunol. 2011 Nov; 166(2):269-80.
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An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma. PLoS One. 2010 Mar 26; 5(3):e9863.
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Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice. J Exp Med. 2008 Apr 14; 205(4):967-79.
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Opposing effects of the D70 mutation and the shared epitope in HLA-DR4 on disease activity and certain disease phenotypes in rheumatoid arthritis. Ann Rheum Dis. 2007 Nov; 66(11):1497-502.