Clostridium botulinum

"Clostridium botulinum" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A species of anaerobic, gram-positive, rod-shaped bacteria in the family Clostridiaceae that produces proteins with characteristic neurotoxicity. It is the etiologic agent of BOTULISM in humans, wild fowl, HORSES; and CATTLE. Seven subtypes (sometimes called antigenic types, or strains) exist, each producing a different botulinum toxin (BOTULINUM TOXINS). The organism and its spores are widely distributed in nature.

Descriptor ID

D003014

MeSH Number(s)

B03.300.390.400.200.160

B03.510.415.400.200.160

Concept/Terms

Clostridium botulinum

Below are MeSH descriptors whose meaning is more general than "Clostridium botulinum".

Organisms [B]
Bacteria [B03]
Endospore-Forming Bacteria [B03.300]
Gram-Positive Endospore-Forming Bacteria [B03.300.390]
Gram-Positive Endospore-Forming Rods [B03.300.390.400]
Clostridium [B03.300.390.400.200]
Clostridium botulinum [B03.300.390.400.200.160]
Gram-Positive Bacteria [B03.510]
Gram-Positive Endospore-Forming Bacteria [B03.510.415]
Gram-Positive Endospore-Forming Rods [B03.510.415.400]
Clostridium [B03.510.415.400.200]
Clostridium botulinum [B03.510.415.400.200.160]

Below are MeSH descriptors whose meaning is more specific than "Clostridium botulinum".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Clostridium botulinum" by people in Harvard Catalyst Profiles by year, and whether "Clostridium botulinum" was a major or minor topic of these publication.

Bar chart showing 16 publications over 13 distinct years, with a maximum of 3 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	1	0	1
2000	1	1	2
2002	0	1	1
2005	1	0	1
2008	0	1	1
2012	0	1	1
2013	1	0	1
2014	1	0	1
2016	1	0	1
2017	3	0	3
2020	0	1	1
2021	1	0	1

Below are the most recent publications written about "Clostridium botulinum" by people in Profiles.

Botulism-like Syndrome Following Botulinum-A Injection for Hyperhidrosis and Fluoroquinolone Use. Can J Neurol Sci. 2022 01; 49(1):154-156.

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BAcTrace, a tool for retrograde tracing of neuronal circuits in Drosophila. Nat Methods. 2020 12; 17(12):1254-1261.

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Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity. Sci Rep. 2018 03 14; 8(1):4518.

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Crystal structures of OrfX2 and P47 from a Botulinum neurotoxin OrfX-type gene cluster. FEBS Lett. 2017 11; 591(22):3781-3792.

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Reversible Association of the Hemagglutinin Subcomplex, HA-33/HA-17 Trimer, with the Botulinum Toxin Complex. Protein J. 2017 10; 36(5):417-424.

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Identification and characterization of a novel botulinum neurotoxin. Nat Commun. 2017 08 03; 8:14130.

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A bacterial global regulator forms a prion. Science. 2017 01 13; 355(6321):198-201.

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"Non-Toxic" Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity. Sci Rep. 2016 08 10; 6:31043.

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N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. Nat Struct Mol Biol. 2016 07; 23(7):656-62.

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Hemagglutinin gene shuffling among Clostridium botulinum serotypes C and D yields distinct sugar recognition of the botulinum toxin complex. Pathog Dis. 2015 Oct; 73(7).

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