HMG-Box Domains

"HMG-Box Domains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)

Descriptor ID

D024742

MeSH Number(s)

G02.111.570.790.709.610.380

Concept/Terms

HMG-Box Domains

Below are MeSH descriptors whose meaning is more general than "HMG-Box Domains".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.790]
Protein Conformation [G02.111.570.790.709]
Protein Structure, Tertiary [G02.111.570.790.709.610]
HMG-Box Domains [G02.111.570.790.709.610.380]

Below are MeSH descriptors whose meaning is related to "HMG-Box Domains".

Below are MeSH descriptors whose meaning is more specific than "HMG-Box Domains".

publications

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This graph shows the total number of publications written about "HMG-Box Domains" by people in Harvard Catalyst Profiles by year, and whether "HMG-Box Domains" was a major or minor topic of these publication.

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Top Journals

J Cell Biol