"Geographic Atrophy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of MACULAR DEGENERATION also known as dry macular degeneration marked by occurrence of a well-defined progressive lesion or atrophy in the central part of the RETINA called the MACULA LUTEA. It is distinguishable from WET MACULAR DEGENERATION in that the latter involves neovascular exudates.
Concept/Terms
Geographic Atrophy- Geographic Atrophy
- Atrophies, Geographic
- Atrophy, Geographic
- Geographic Atrophies
- Dry Macular Degeneration
- Degeneration, Dry Macular
- Degenerations, Dry Macular
- Dry Macular Degenerations
- Macular Degeneration, Dry
- Macular Degenerations, Dry
Below are MeSH descriptors whose meaning is more general than "Geographic Atrophy".
Below are MeSH descriptors whose meaning is more specific than "Geographic Atrophy".
This graph shows the total number of publications written about "Geographic Atrophy" by people in Harvard Catalyst Profiles by year, and whether "Geographic Atrophy" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 2 | 2 | 4 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 1 | 3 |
| 2013 | 4 | 1 | 5 |
| 2014 | 2 | 2 | 4 |
| 2015 | 3 | 1 | 4 |
| 2016 | 3 | 0 | 3 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 4 | 0 | 4 |
| 2020 | 2 | 0 | 2 |
| 2021 | 3 | 2 | 5 |
| 2022 | 4 | 0 | 4 |
| 2023 | 5 | 0 | 5 |
Below are the most recent publications written about "Geographic Atrophy" by people in Profiles.
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Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials. Lancet. 2023 10 21; 402(10411):1434-1448.
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Treatment of geographic atrophy: an update on data related to pegcetacoplan. Curr Opin Ophthalmol. 2024 Jan 01; 35(1):64-72.
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A Cost-Effectiveness Analysis of Pegcetacoplan for the Treatment of Geographic Atrophy. Ophthalmol Retina. 2024 Jan; 8(1):25-31.
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COMPLEMENT INHIBITION FOR GEOGRAPHIC ATROPHY: Review of Salient Functional Outcomes and Perspective. Retina. 2023 07 01; 43(7):1064-1069.
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Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial. Eye (Lond). 2023 12; 37(17):3551-3557.
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Color Vision and Microperimetry Changes in Nonexudative Age-Related Macular Degeneration After Risuteganib Treatment: Exploratory Endpoints in a Multicenter Phase 2a Double-Masked, Randomized, Sham-Controlled, Crossover Clinical Trial. Ophthalmic Surg Lasers Imaging Retina. 2022 08; 53(8):430-438.
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Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration. Nat Commun. 2022 07 26; 13(1):4233.
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Cell culture models to study retinal pigment epithelium-related pathogenesis in age-related macular degeneration. Exp Eye Res. 2022 09; 222:109170.
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Severity of age-related macular degeneration at first presentation in Bhutan: a 3-year national study. BMC Ophthalmol. 2022 Jul 09; 22(1):298.
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Intraocular iron injection induces oxidative stress followed by elements of geographic atrophy and sympathetic ophthalmia. Aging Cell. 2021 11; 20(11):e13490.