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1-Methyl-4-phenylpyridinium

"1-Methyl-4-phenylpyridinium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
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An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.


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This graph shows the total number of publications written about "1-Methyl-4-phenylpyridinium" by people in Harvard Catalyst Profiles by year, and whether "1-Methyl-4-phenylpyridinium" was a major or minor topic of these publication.
Bar chart showing 19 publications over 13 distinct years, with a maximum of 3 publications in 2004
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.