Peptide Chain Initiation, Translational
"Peptide Chain Initiation, Translational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A process of GENETIC TRANSLATION whereby the formation of a peptide chain is started. It includes assembly of the RIBOSOME components, the MESSENGER RNA coding for the polypeptide to be made, INITIATOR TRNA, and PEPTIDE INITIATION FACTORS; and placement of the first amino acid in the peptide chain. The details and components of this process are unique for prokaryotic protein biosynthesis and eukaryotic protein biosynthesis.
MeSH Number(s)
G02.111.087.675.871.650
G02.149.115.675.871.650
G03.495.770.871.650
Concept/Terms
Peptide Chain Initiation, Translational- Peptide Chain Initiation, Translational
- Protein Biosynthesis Initiation
- Biosynthesis Initiation, Protein
- Initiation, Protein Biosynthesis
- Protein Chain Initiation, Translational
- Translation Initiation, Genetic
- Genetic Translation Initiation
- Initiation, Genetic Translation
- Translational Initiation, Protein
- Initiation, Protein Translational
- Protein Translational Initiation
- Translational Peptide Chain Initiation
- Protein Translation Initiation
- Chain Initiation, Peptide, Translational
- Translation Initiation, Protein
- Initiation, Protein Translation
Below are MeSH descriptors whose meaning is more general than "Peptide Chain Initiation, Translational".
Below are MeSH descriptors whose meaning is more specific than "Peptide Chain Initiation, Translational".
This graph shows the total number of publications written about "Peptide Chain Initiation, Translational" by people in Harvard Catalyst Profiles by year, and whether "Peptide Chain Initiation, Translational" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 4 | 5 |
| 1997 | 0 | 2 | 2 |
| 1998 | 2 | 2 | 4 |
| 2000 | 0 | 2 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 4 | 1 | 5 |
| 2012 | 4 | 2 | 6 |
| 2013 | 3 | 1 | 4 |
| 2015 | 2 | 1 | 3 |
| 2016 | 4 | 0 | 4 |
| 2017 | 2 | 2 | 4 |
| 2018 | 2 | 0 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 2 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Peptide Chain Initiation, Translational" by people in Profiles.
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A paradoxical genotype-phenotype relationship: Low level of GOSR2 translation from a non-AUG start codon in a family with profound hearing loss. Hum Mol Genet. 2023 07 04; 32(14):2265-2268.
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The metaphorical swiss army knife: The multitude and diverse roles of HEAT domains in eukaryotic translation initiation. Nucleic Acids Res. 2022 06 10; 50(10):5424-5442.
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Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation. Proc Natl Acad Sci U S A. 2021 02 09; 118(6).
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Translation elongation rate varies among organs and decreases with age. Nucleic Acids Res. 2021 01 25; 49(2):e9.
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GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control. Mol Cell. 2020 09 17; 79(6):950-962.e6.
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Selective translation by alternative bacterial ribosomes. Proc Natl Acad Sci U S A. 2020 08 11; 117(32):19487-19496.
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eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function. Nucleic Acids Res. 2020 06 19; 48(11):6223-6233.
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Inverted translational control of eukaryotic gene expression by ribosome collisions. PLoS Biol. 2019 09; 17(9):e3000396.
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Comprehensive profiling of translation initiation in influenza virus infected cells. PLoS Pathog. 2019 01; 15(1):e1007518.
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Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells. Nat Chem Biol. 2018 09; 14(9):844-852.