Quisqualic Acid

"Quisqualic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of Quisqualis chinensis.

Descriptor ID

D016318

MeSH Number(s)

D03.383.129.462.580.600

D12.125.755

Concept/Terms

Quisqualic Acid

Quisqualate

Below are MeSH descriptors whose meaning is more general than "Quisqualic Acid".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Oxazoles [D03.383.129.462]
Oxadiazoles [D03.383.129.462.580]
Quisqualic Acid [D03.383.129.462.580.600]
Amino Acids, Peptides, and Proteins [D12]
Amino Acids [D12.125]
Quisqualic Acid [D12.125.755]

Below are MeSH descriptors whose meaning is more specific than "Quisqualic Acid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Quisqualic Acid" by people in Harvard Catalyst Profiles by year, and whether "Quisqualic Acid" was a major or minor topic of these publication.

Bar chart showing 10 publications over 6 distinct years, with a maximum of 3 publications in 1997

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1994	2	2
1995	2	2
1997	3	3
2007	1	1
2008	1	1
2013	1	1

Below are the most recent publications written about "Quisqualic Acid" by people in Profiles.

Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1a. J Biol Chem. 2014 Jan 17; 289(3):1649-61.

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Dermatomal scratching after intramedullary quisqualate injection: correlation with cutaneous denervation. J Pain. 2008 Nov; 9(11):999-1005.

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Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC). J Pharmacol Exp Ther. 2007 Jun; 321(3):1144-53.

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Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for inhibition and disinhibition of neuronal networks. J Neurosci. 2000 Jan 01; 20(1):66-75.

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Selective metabotropic receptor agonists distinguish non-ionotropic glutamate binding sites. Brain Res. 1997 Oct 31; 773(1-2):15-27.

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Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain. J Neurochem. 1997 Aug; 69(2):704-12.

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Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype. Neuropharmacology. 1997 Jul; 36(7):917-31.

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In vitro and in vivo antagonism of AMPA receptor activation by (3S, 4aR, 6R, 8aR)-6-[2-(1(2)H-tetrazole-5-yl) ethyl] decahydroisoquinoline-3-carboxylic acid. Neuropharmacology. 1995 Sep; 34(9):1159-68.

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Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors. Proc Natl Acad Sci U S A. 1995 Aug 15; 92(17):8083-7.

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Neurotoxicity of acute glutamate transport blockade depends on coactivation of both NMDA and AMPA/Kainate receptors in organotypic hippocampal cultures. Exp Neurol. 1995 May; 133(1):7-17.

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