Blood-Testis Barrier

"Blood-Testis Barrier" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A specialized barrier, in the TESTIS, between the interstitial BLOOD compartment and the adluminal compartment of the SEMINIFEROUS TUBULES. The barrier is formed by layers of cells from the VASCULAR ENDOTHELIUM of the capillary BLOOD VESSELS, to the SEMINIFEROUS EPITHELIUM of the seminiferous tubules. TIGHT JUNCTIONS form between adjacent SERTOLI CELLS, as well as between the ENDOTHELIAL CELLS.

Descriptor ID

D001814

MeSH Number(s)

A05.360.444.849.700.349

A07.045

Concept/Terms

Blood-Testis Barrier

Below are MeSH descriptors whose meaning is more general than "Blood-Testis Barrier".

Anatomy [A]
Urogenital System [A05]
Genitalia [A05.360]
Genitalia, Male [A05.360.444]
Testis [A05.360.444.849]
Seminiferous Tubules [A05.360.444.849.700]
Blood-Testis Barrier [A05.360.444.849.700.349]
Cardiovascular System [A07]
Blood-Testis Barrier [A07.045]

Below are MeSH descriptors whose meaning is related to "Blood-Testis Barrier".

Below are MeSH descriptors whose meaning is more specific than "Blood-Testis Barrier".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Blood-Testis Barrier" by people in Harvard Catalyst Profiles by year, and whether "Blood-Testis Barrier" was a major or minor topic of these publication.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2012 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	1	0	1
2012	1	1	2
2014	1	0	1
2015	1	1	2
2019	0	1	1
2020	1	0	1

Below are the most recent publications written about "Blood-Testis Barrier" by people in Profiles.

Distribution pattern of ZO-1 and claudins in the epididymis of vampire bats. Tissue Barriers. 2020 07 02; 8(3):1779526.

View in: PubMed
Positron emission tomography probes targeting bromodomain and extra-terminal (BET) domains to enable in vivo neuroepigenetic imaging. Chem Commun (Camb). 2019 Oct 24; 55(86):12932-12935.

View in: PubMed
Regulatory and junctional proteins of the blood-testis barrier in human Sertoli cells are modified by monobutyl phthalate (MBP) and bisphenol A (BPA) exposure. Toxicol In Vitro. 2016 Aug; 34:1-7.

View in: PubMed
AKAP9, a Regulator of Microtubule Dynamics, Contributes to Blood-Testis Barrier Function. Am J Pathol. 2016 Feb; 186(2):270-84.

View in: PubMed
The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis. Biol Reprod. 2016 Jan; 94(1):22.

View in: PubMed
Exploring the role of mononuclear phagocytes in the epididymis. Asian J Androl. 2015 Jul-Aug; 17(4):591-6.

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N-wasp is required for structural integrity of the blood-testis barrier. PLoS Genet. 2014 Jun; 10(6):e1004447.

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Small-molecule inhibition of BRDT for male contraception. Cell. 2012 Aug 17; 150(4):673-84.

View in: PubMed
Nanoparticles and spermatogenesis: how do nanoparticles affect spermatogenesis and penetrate the blood-testis barrier. Nanomedicine (Lond). 2012 Apr; 7(4):579-96.

View in: PubMed
Adenomatous polyposis coli (APC) is essential for maintaining the integrity of the seminiferous epithelium. Mol Endocrinol. 2011 Oct; 25(10):1725-39.

View in: PubMed

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