"Cholestanols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cholestanes substituted in any position with one or more hydroxy groups. They are found in feces and bile. In contrast to bile acids and salts, they are not reabsorbed.
Concept/Terms
Cholestanols- Cholestanols
- Hydroxycholestanes
- Bile Alcohols
- Alcohols, Bile
Below are MeSH descriptors whose meaning is more general than "Cholestanols".
Below are MeSH descriptors whose meaning is more specific than "Cholestanols".
This graph shows the total number of publications written about "Cholestanols" by people in Harvard Catalyst Profiles by year, and whether "Cholestanols" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2003 | 2 | 0 | 2 |
2005 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
Below are the most recent publications written about "Cholestanols" by people in Profiles.
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Selective screening of Niemann-Pick type C Brazilian patients by cholestane-3ß,5a,6ß-triol and chitotriosidase measurements followed by filipin staining and NPC1/NPC2 gene analysis. Clin Chim Acta. 2016 Aug 01; 459:57-62.
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Towards squalamine mimics: synthesis and antibacterial activities of head-to-tail dimeric sterol-polyamine conjugates. Chem Biodivers. 2013 Mar; 10(3):385-93.
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A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma. J Lipid Res. 2011 07; 52(7):1435-45.
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A bioconjugate approach toward squalamine mimics: Insight into the mechanism of biological action. Bioconjug Chem. 2006 Nov-Dec; 17(6):1582-91.
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Apparent receptor-mediated activation of Ca2+-dependent conductive Cl- transport by shark-derived polyaminosterols. Am J Physiol Regul Integr Comp Physiol. 2005 Dec; 289(6):R1644-58.
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A phase I/IIA trial of continuous five-day infusion of squalamine lactate (MSI-1256F) plus carboplatin and paclitaxel in patients with advanced non-small cell lung cancer. Clin Cancer Res. 2003 Sep 15; 9(11):4108-15.
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A Phase I and pharmacokinetic study of squalamine, an aminosterol angiogenesis inhibitor. Clin Cancer Res. 2003 Jul; 9(7):2465-71.
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Differential inhibition of AE1 and AE2 anion exchangers by oxonol dyes and by novel polyaminosterol analogs of the shark antibiotic squalamine. Biochem Cell Biol. 1998; 76(5):799-806.
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Aziridinyl steroid-induced lesions in DNA and apoptosis in promyelocytic leukemia cells. Biochem Mol Biol Int. 1997 Dec; 43(6):1353-65.
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Mutagenic activity of aziridinyl steroids and their mechanism of action in biological systems. Mutagenesis. 1991 Jul; 6(4):271-8.