Receptors, Purinergic P2Y1
"Receptors, Purinergic P2Y1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of purinergic P2Y receptors that have a preference for ATP and ADP. The activated P2Y1 receptor signals through the G-PROTEIN-coupled activation of PHOSPHOLIPASE C and mobilization of intracellular CALCIUM.
MeSH Number(s)
D12.776.543.750.100.700.720.500.100
D12.776.543.750.720.700.720.750.100
D12.776.543.750.810.720.750.100
Concept/Terms
Receptors, Purinergic P2Y1- Receptors, Purinergic P2Y1
- P2Y1 Receptors, Purinergic
- Purinergic P2Y1 Receptors
- P2Y1 Purinoceptors
- Purinoceptors, P2Y1
- P2Y1 Receptor
- Receptor, P2Y1
- Purinergic Receptor P2Y, G-Protein Coupled, 1
- Purinoceptor P2Y1
- P2Y1 Purinoceptor
- Purinoceptor, P2Y1
- P2Y1 Receptors
- Receptors, P2Y1
Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2Y1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Purinergic [D12.776.543.750.100.700]
- Receptors, Purinergic P2 [D12.776.543.750.100.700.720]
- Receptors, Purinergic P2Y [D12.776.543.750.100.700.720.500]
- Receptors, Purinergic P2Y1 [D12.776.543.750.100.700.720.500.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2Y [D12.776.543.750.720.700.720.750]
- Receptors, Purinergic P2Y1 [D12.776.543.750.720.700.720.750.100]
- Receptors, Purinergic [D12.776.543.750.810]
- Receptors, Purinergic P2 [D12.776.543.750.810.720]
- Receptors, Purinergic P2Y [D12.776.543.750.810.720.750]
- Receptors, Purinergic P2Y1 [D12.776.543.750.810.720.750.100]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2Y1".
This graph shows the total number of publications written about "Receptors, Purinergic P2Y1" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Purinergic P2Y1" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 1 | 2 |
| 2014 | 3 | 0 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 1 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Purinergic P2Y1" by people in Profiles.
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The cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients. Sci Rep. 2021 10 05; 11(1):19752.
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An Airway Protection Program Revealed by Sweeping Genetic Control of Vagal Afferents. Cell. 2020 04 30; 181(3):574-589.e14.
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Bioinformatics Screening of Genes Specific for Well-Regenerating Vertebrates Reveals c-answer, a Regulator of Brain Development and Regeneration. Cell Rep. 2019 10 22; 29(4):1027-1040.e6.
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Autocrine stimulation of P2Y1 receptors is part of the purinergic signaling mechanism that regulates T cell activation. Purinergic Signal. 2019 06; 15(2):127-137.
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GLS-409, an Antagonist of Both P2Y1 and P2Y12, Potently Inhibits Canine Coronary Artery Thrombosis and Reversibly Inhibits Human Platelet Activation. Sci Rep. 2018 09 28; 8(1):14529.
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KV 7/M channels as targets for lipopolysaccharide-induced inflammatory neuronal hyperexcitability. J Physiol. 2017 02 01; 595(3):713-738.
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Simultaneous Platelet P2Y12 and P2Y1 ADP Receptor Blockade: Are Two Better Than One? Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):427-8.
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Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):501-9.
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New highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 adenosine diphosphate receptors. Eur J Med Chem. 2016 Jan 01; 107:204-18.
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P2Y(1) receptor mediated neuronal fibre outgrowth in organotypic brain slice co-cultures. Neuropharmacology. 2015 Jun; 93:252-66.