Trypanosoma brucei rhodesiense

"Trypanosoma brucei rhodesiense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A hemoflagellate subspecies of parasitic protozoa that causes Rhodesian sleeping sickness in humans. It is carried by Glossina pallidipes, G. morsitans and occasionally other species of game-attacking tsetse flies.

Descriptor ID

D016833

MeSH Number(s)

B01.268.475.868.887.115

Concept/Terms

Trypanosoma brucei rhodesiense

Below are MeSH descriptors whose meaning is more general than "Trypanosoma brucei rhodesiense".

Organisms [B]
Eukaryota [B01]
Euglenozoa [B01.268]
Kinetoplastida [B01.268.475]
Trypanosomatina [B01.268.475.868]
Trypanosoma [B01.268.475.868.887]
Trypanosoma brucei rhodesiense [B01.268.475.868.887.115]

Below are MeSH descriptors whose meaning is related to "Trypanosoma brucei rhodesiense".

Below are MeSH descriptors whose meaning is more specific than "Trypanosoma brucei rhodesiense".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Trypanosoma brucei rhodesiense" by people in Harvard Catalyst Profiles by year, and whether "Trypanosoma brucei rhodesiense" was a major or minor topic of these publication.

Bar chart showing 7 publications over 6 distinct years, with a maximum of 2 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2005	0	1	1
2010	1	0	1
2014	0	2	2
2016	0	1	1
2020	0	1	1

Below are the most recent publications written about "Trypanosoma brucei rhodesiense" by people in Profiles.

Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity. J Med Chem. 2020 01 23; 63(2):847-879.

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Structural characterization of the C-terminal coiled-coil domains of wild-type and kidney disease-associated mutants of apolipoprotein L1. FEBS J. 2016 05; 283(10):1846-62.

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Sequencing rare and common APOL1 coding variants to determine kidney disease risk. Kidney Int. 2015 Oct; 88(4):754-63.

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Evolution of the primate trypanolytic factor APOL1. Proc Natl Acad Sci U S A. 2014 May 20; 111(20):E2130-9.

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Substituted 2-phenylimidazopyridines: a new class of drug leads for human African trypanosomiasis. J Med Chem. 2014 Feb 13; 57(3):828-35.

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Identification of Trypanosome proteins in plasma from African sleeping sickness patients infected with T. b. rhodesiense. PLoS One. 2013; 8(8):e71463.

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Using detergent to enhance detection sensitivity of African trypanosomes in human CSF and blood by loop-mediated isothermal amplification (LAMP). PLoS Negl Trop Dis. 2011 Aug; 5(8):e1249.

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Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science. 2010 Aug 13; 329(5993):841-5.

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Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells. PLoS Negl Trop Dis. 2009 Jul 21; 3(7):e479.

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Trypanocidal activity of 8-methyl-5'-{[(Z)-4-aminobut-2-enyl]-(methylamino)}adenosine (Genz-644131), an adenosylmethionine decarboxylase inhibitor. Antimicrob Agents Chemother. 2009 Aug; 53(8):3269-72.

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PLoS Negl Trop Dis
Antimicrob Agents Chemother
Science
PLoS One
N Engl J Med
Clin Exp Immunol
J Med Chem
Kidney Int
J Clin Invest
FEBS J