"Heparin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
Concept/Terms
Heparin- Heparin
- Unfractionated Heparin
- Heparin, Unfractionated
- Heparinic Acid
Below are MeSH descriptors whose meaning is more general than "Heparin".
Below are MeSH descriptors whose meaning is more specific than "Heparin".
This graph shows the total number of publications written about "Heparin" by people in Harvard Catalyst Profiles by year, and whether "Heparin" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 6 | 14 | 20 |
1995 | 11 | 12 | 23 |
1996 | 19 | 13 | 32 |
1997 | 15 | 14 | 29 |
1998 | 16 | 16 | 32 |
1999 | 20 | 11 | 31 |
2000 | 15 | 22 | 37 |
2001 | 18 | 24 | 42 |
2002 | 12 | 17 | 29 |
2003 | 15 | 15 | 30 |
2004 | 16 | 22 | 38 |
2005 | 11 | 16 | 27 |
2006 | 17 | 16 | 33 |
2007 | 19 | 17 | 36 |
2008 | 23 | 12 | 35 |
2009 | 8 | 9 | 17 |
2010 | 13 | 10 | 23 |
2011 | 10 | 6 | 16 |
2012 | 5 | 10 | 15 |
2013 | 10 | 4 | 14 |
2014 | 14 | 17 | 31 |
2015 | 11 | 8 | 19 |
2016 | 18 | 10 | 28 |
2017 | 22 | 6 | 28 |
2018 | 14 | 9 | 23 |
2019 | 17 | 6 | 23 |
2020 | 14 | 12 | 26 |
2021 | 17 | 16 | 33 |
2022 | 7 | 14 | 21 |
2023 | 5 | 11 | 16 |
2024 | 1 | 2 | 3 |
Below are the most recent publications written about "Heparin" by people in Profiles.
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Bivalirudin: The misunderstood alternative to heparin. Paediatr Anaesth. 2024 05; 34(5):394-395.
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Structural insights into the formation of repulsive netrin guidance complexes. Sci Adv. 2024 Feb 16; 10(7):eadj8083.
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Finding a common definition of heparin resistance in adult cardiac surgery: communication from the ISTH SSC subcommittee on perioperative and critical care thrombosis and hemostasis. J Thromb Haemost. 2024 Apr; 22(4):1249-1257.
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Direct thrombin inhibitors fail to reverse the negative effects of heparin on lung growth and function after murine left pneumonectomy. Am J Physiol Lung Cell Mol Physiol. 2024 Mar 01; 326(3):L213-L225.
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Platelet Factor 4 Antibodies and Severe AKI. Kidney360. 2023 12 01; 4(12):1672-1679.
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The impact of urgency of repair on outcomes following thoracic endovascular aortic repair for blunt thoracic aortic injury. J Vasc Surg. 2024 Feb; 79(2):229-239.e3.
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Bivalirudin Versus Heparin During PCI in NSTEMI: Individual Patient Data Meta-Analysis of Large Randomized Trials. Circulation. 2023 10 17; 148(16):1207-1219.
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One-year clinical outcomes of bivalirudin versus unfractionated heparin in patients with type 2 diabetes undergoing elective percutaneous coronary intervention. Diabetes Metab Syndr. 2023 Oct; 17(10):102858.
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Defining heparin resistance: communication from the ISTH SSC Subcommittee of Perioperative and Critical Care Thrombosis and Hemostasis. J Thromb Haemost. 2023 12; 21(12):3649-3657.
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Low-molecular-weight heparin is superior to unfractionated heparin in lowering the risk of venous thromboembolism after traumatic lower extremity amputation. Surgery. 2023 10; 174(4):1026-1033.